International (Pediatric) Peritoneal Biobank

Launched by HEIDELBERG UNIVERSITY · Jul 2, 2013

Keywords

ClinConnect Summary

The International Pediatric Peritoneal Biobank trial is studying changes in the peritoneal membrane, which is important for children undergoing peritoneal dialysis (PD) due to kidney failure. This trial aims to collect tissue samples from children on PD to understand how their bodies react to the treatment and how these changes might affect their health. The researchers will gather these samples during routine medical procedures, like inserting a PD catheter or during surgeries, ensuring that the process is safe and does not significantly increase the risk of surgery.

To participate in this study, children and adults between the ages of 0 and 90 who are on PD or undergoing certain elective abdominal surgeries may be eligible. Participants will need to provide consent, and for younger patients, their parents or guardians will need to agree as well. By joining this trial, participants can help researchers learn more about the effects of PD on the body, which may lead to better treatment options in the future. This study is currently recruiting participants and is focused on understanding both the immediate and long-term impacts of PD on children’s health.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • Age 0 to 90 years
• • CKD 5D, peritoneal dialysis and
• • Patients with normal renal function and elective abdominal surgery due to limited abdominal pathology (such as hernia repair, gallstones....)
• • Patients post PD and post Tx
• • Oral and written consent
• • Ability to consent of the adult patient and of the parents and legal guardian of patients not yet of legal age, respectively
• Exclusion Criteria:
• • Abdominal adhesions, malformation and inflammation beyond PD induced changes
• • Patients with disseminated tumour disease
• • Patients with critical heart failure and other medical conditions, where the additional procedure may confer an increased increase risk
• • Pregnancy
• • Preterm babies (below 37 weeks of gestational age)
• • Serum hemoglobin \< 10 g/dl in newborns and \< 8 g/dl in children and adults