Correlation of Artherosclerotic Plaque Volume and Intima Media Thickness With Soluble P-selectin

Launched by MEDICAL UNIVERSITY INNSBRUCK · Jul 5, 2013

Keywords

ClinConnect Summary

This clinical trial is studying how certain factors relate to the progression of atherosclerosis, which is the buildup of plaque in the arteries that can lead to serious heart and blood vessel problems. Researchers will follow 600 patients who have cardiovascular disease or at least one risk factor, such as high blood pressure, smoking, diabetes, or a family history of heart disease. Over four years, patients will undergo yearly ultrasound scans to measure changes in their carotid arteries and provide blood samples to test for various risk factors.

To be eligible for this study, participants need to be between 30 and 85 years old and have at least one traditional risk factor or an existing diagnosis of heart-related conditions. Throughout the study, participants can expect regular check-ups and to help researchers understand how things like P-selectin, a protein in the blood, might relate to the progression of atherosclerosis. This research aims to identify new ways to predict heart disease and improve patient care.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients (male and female) aged 30 to 85 years
• • with at least one traditional cardiovascular risk factor (hypertension, smoking, diabetes, dyslipidemia, family history) or established coronary artery disease, cerebrovascular disease, or peripheral artery disease diagnosed by objective testing
• Exclusion Criteria:
• • lack of informed consent
• • the impossibility of follow-up testing once per year for the following four years