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Search / Trial NCT01897584

Effect Inverse Ratio Ventilation on Arterial Oxygenation and Respiratory Mechanics During lapaLAR

Launched by GACHON UNIVERSITY GIL MEDICAL CENTER · Jul 9, 2013

Trial Information

Current as of August 21, 2025

Completed

Keywords

Laparoscopy, Trendelenburg Position, Ventilation

ClinConnect Summary

Inverse ratio ventilation already known as effective to improve the oxygenation and respiratory mechanics in the ARDS patients. Recently, there were report of decrease in airway pressure and improve in respiratory compliance during inverse ration ventilation undergoing one lung ventilation. We hypothesized that changes of inspiration and expiration ratio from 1:2 to 1:1 could improve the arterial oxygenation and respiratory mechanics in the patients who undergoing laparoscopic low anterior resection. However, prolonged inspiratory time might compromise cerebral perfusion pressure due to an ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • colorectal cancer
  • Exclusion Criteria:
  • obesity (BMI\>35), uncontrolled hypertension, coronary artery disease, uncompensated cardiovascular disease, current respiratory disease, open procedure

About Gachon University Gil Medical Center

Gachon University Gil Medical Center is a leading healthcare institution located in South Korea, renowned for its commitment to advancing medical research and clinical excellence. As a prominent clinical trial sponsor, the center leverages its comprehensive expertise in various medical fields to facilitate innovative research initiatives aimed at improving patient outcomes. With a strong focus on collaboration, Gachon University Gil Medical Center engages in partnerships with academic institutions, industry leaders, and healthcare professionals to drive the development of groundbreaking therapies and treatment modalities. Its state-of-the-art facilities and dedicated research teams ensure rigorous adherence to ethical standards and regulatory compliance, positioning the center at the forefront of clinical research in the region.

Locations

Incheon, , Korea, Republic Of

Patients applied

0 patients applied

Trial Officials

Hyun Jeong Kwak, M.D., Ph.D

Study Director

Gachon University Gil Medical Center

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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