Chest Physiotherapy and Lung Function in Primary Ciliary Dyskinesia
Launched by UNIVERSITAIRE ZIEKENHUIZEN KU LEUVEN · Aug 22, 2013
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of chest physiotherapy on lung function in patients with a rare condition called primary ciliary dyskinesia (PCD). PCD affects the tiny hair-like structures in the body that help clear mucus from the lungs, leading to frequent respiratory infections. The researchers want to understand if chest physiotherapy, a treatment that helps clear mucus from the lungs, can improve how well the lungs work both in the short and long term. They believe that having a session of this therapy might lead to better lung function, so they will conduct tests in a consistent way to measure this.
To participate in the trial, individuals must be diagnosed with primary ciliary dyskinesia and be at least 6 years old, as they need to be able to perform specific lung tests. However, those currently experiencing a severe flare-up of their condition will not be eligible. Participants will receive chest physiotherapy and undergo lung function tests to see how the therapy affects their breathing. The trial is currently recruiting participants of all genders, and it aims to provide valuable insights that could help improve treatment for people with PCD.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Primary ciliary dyskinesia
- • able to perform spirometry and MBW (\>6 years)
- Exclusion Criteria:
- • acute exacerbation
About Universitaire Ziekenhuizen Ku Leuven
Universitaire Ziekenhuizen KU Leuven is a leading academic medical center in Belgium, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. Affiliated with KU Leuven, one of Europe’s premier universities, the institution integrates cutting-edge scientific inquiry with high-quality patient care. It plays a pivotal role in the development and implementation of clinical trials, fostering collaboration between researchers, healthcare professionals, and industry partners to translate scientific discoveries into effective treatments. The hospital's multidisciplinary approach ensures comprehensive patient safety and ethical standards, positioning it as a trusted sponsor in the realm of clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Leuven, , Belgium
Patients applied
Trial Officials
Mieke Boon, MD
Principal Investigator
research fellow
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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