Quantitative MRI for Myelofibrosis

Launched by UNIVERSITY OF MICHIGAN · Oct 25, 2013

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to use MRI scans to help understand and track myelofibrosis, a type of bone marrow disease. The goal is to develop and test specific MRI techniques that can measure how advanced the disease is and how well patients are responding to treatments. Researchers hope that these new MRI methods will give important information that can guide better care for people with myelofibrosis.

To participate in this study, you need to be an adult over 18 years old and have been diagnosed with myelofibrosis, which can either be primary or related to other blood disorders. You’ll also need to be able to have an MRI scan without needing anesthesia and not have any medical devices like pacemakers that could be affected by the MRI’s strong magnetic field. If you join the trial, you can expect to undergo MRI scans that will help researchers learn more about your condition and treatment response. Overall, this study aims to improve how myelofibrosis is monitored and treated in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Male /female subjects over the age of 18
• • 2. Diagnosis of primary myelofibrosis, post-polycythemia vera myelofibrosis, or post-essential thrombocythemia myelofibrosis.
• • 3. No contraindications to MRI
• • 4. Able to undergo MRI without anesthesia
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• Exclusion Criteria:
• • 1. Patients with pacemakers or other implanted magnetic devices that may malfunction or move because of the strong magnetic field inside the MRI room and scanner.
• • 2. Any prior adverse event associated with MRI that is not related to injection of contrast agents or other medicines.
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