Optical Coherence Tomography (OCT) in Uveitis

Launched by OREGON HEALTH AND SCIENCE UNIVERSITY · Dec 30, 2013

Keywords

ClinConnect Summary

This clinical trial is studying the use of Optical Coherence Tomography (OCT), a special imaging technology, to better understand uveitis, which is inflammation of parts of the eye. The OCT machine takes detailed pictures of the eye's inner structures, helping doctors see the white blood cells and inflammation that occur in uveitis. Researchers hope that this technology will improve diagnosis and treatment for patients with various types of uveitis.

To participate in the trial, you need to be at least 18 years old and have specific signs of uveitis, such as certain levels of inflammatory cells in the eye or other related conditions like blood in the eye or retinal tears. If you decide to join, you can expect to undergo OCT imaging, which is a painless procedure that doesn’t involve any contact with your eye. It's important to note that participants must be able to give consent and keep their eyes steady during the imaging process. If you or a family member are dealing with uveitis, this trial could provide valuable information and potentially lead to better ways to manage the condition.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age and older
• * With one or more of the following clinical features:
• • 1. \>1+ AC cells;
• • 2. \>1+ vitreous haze;
• • 3. presence of vitreous cells;
• • 4. presence of blood in anterior chamber;
• • 5. presence of blood in vitreous;
• • 6. presence of aqueous or vitreous pigment.
• * In one of the following diagnostic categories as determined by a uveitis specialists:
• • 1. uveitis due to ankylosing spondylitis (positive HLA B27 genotype);
• • 2. uveitis due to sarcoidosis;
• • 3. uveitis of any additional type;
• • 4. uveitis masquerade such as pigment dispersion syndrome or Schaffer's sign;
• • 5. hyphema due to trauma or other causes;
• • 6. vitreous hemorrhage;
• • 7. retinal tear.
• Exclusion Criteria:
• • Inability to give informed consent;
• • Inability to maintain stable fixation for OCT imaging.