Single-step Versus Sequential Media in Preimplantation Embryo Development and Pregnancy Rates
Launched by EUGONIA · Jan 27, 2014
Trial Information
Current as of July 21, 2025
Completed
Keywords
ClinConnect Summary
Sequential culture media were introduced in order to meet the changing requirements of the developing embryo in vitro. However, there has been renewed interest in the use of single-step media, which allow the embryo itself to choose the necessary nutrients while maintaining a more stable culture environment. Previous studies suggest that sequential media do not appear superior to single-step media.
The current study will include 2 RCTs:
RCT 1: Random allocation of sibling oocytes to compare embryo development and blastocyst formation rates in the two culture media compared.
RCT2: Random ...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • \<40 years of age
- • female infertility patients
- • at least 10 retrieved oocytes
- Exclusion Criteria:
- • 41 years or older
- • frozen-thawed oocytes/embryos
- • oocyte donation cycles
About Eugonia
Eugonia is a pioneering clinical trial sponsor dedicated to advancing innovative therapeutic solutions in the field of regenerative medicine. With a commitment to enhancing patient outcomes, Eugonia specializes in the development and execution of cutting-edge clinical trials that focus on harnessing the body's natural healing processes. The organization is driven by a team of experienced professionals who prioritize scientific integrity, patient safety, and regulatory compliance. By fostering collaborations with leading research institutions and healthcare providers, Eugonia aims to accelerate the translation of groundbreaking research into effective treatments, ultimately improving the quality of life for patients worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Athens, Attica, Greece
Patients applied
Trial Officials
Ioannis A Sfontouris, PhD
Principal Investigator
Eugonia
Trifon G Lainas, PhD
Study Director
Eugonia
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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