Pathogenic Mechanisms of Port Wine Stain and Repository of Port Wine Stain Biopsy Samples

Launched by UNIVERSITY OF CALIFORNIA, IRVINE · Jan 29, 2014

Keywords

ClinConnect Summary

The researcher can detect the defects in nervous system innervation to cutaneous blood vessels contribute to the pathogenesis of Port Wine Stain . Unveiling the pathogenic mechanisms of PWS is crucial to the design of new therapeutic strategies and can use the results to improve current PWS therapeutic outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female of all ages.
• • Not pregnant.
• • Has diagnosis of port wine stain on the arms, legs, chest, bac.
• • Ability to understand and carry out subject instructions.
• • Subject willing to have skin biopsies on port wine stain and normal skin areas.
• Exclusion Criteria:
• • Pregnant women.
• • Port Wine Stain on the face.
• • History of skin cancer.
• • Current participation in an investigational drug evaluation
• • Concurrent use of known photosensitizing drugs.