Efficacy of Cyclic DSG Compared With Cyclic MPA for the Treatment of Anovulatory DUB
Launched by MAHIDOL UNIVERSITY · Apr 1, 2014
Trial Information
Current as of May 19, 2025
Unknown status
Keywords
ClinConnect Summary
Anovulatory dysfunctional uterine bleeding (DUB) is the most common cause of abnormal uterine bleeding especially in postmenarcheal adolescent, perimenopausal women, patient with polycystic ovary syndrome (PCOS) and in obese women. Aims of treatment in women with anovulatory DUB are to restore the natural control mechanism of endometrium (introduce normal synchronous growth, development, shedding of a structural stable endometrium) and to prevent endometrial hyperplasia. The two main treatment options are estrogen-progestin therapy and progestin therapy. Women who are sexually active and no...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Premenopausal women with anovular DUB (proved by endometrial histology)
- • Age \> 18 yr.
- Exclusion Criteria:
- • Any uterine pathology that might cause abnormal uterine bleeding
- • Contraindication to progestin treatment (such as breast cancer)
- • Severe drug allergy towards a progestogen
- • Intake of any hormonal treatment in the previous 3 months
About Mahidol University
Mahidol University, a premier institution in Thailand, is dedicated to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the university leverages its extensive expertise in medical and health sciences to facilitate rigorous scientific investigations aimed at improving patient care and public health outcomes. With a commitment to ethical practices and collaboration, Mahidol University fosters multidisciplinary approaches, engaging a diverse array of researchers and healthcare professionals to drive meaningful advancements in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bangkok, , Thailand
Patients applied
Trial Officials
Manee Rattanachaiyanont, M.D.
Principal Investigator
Mahidol University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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