Behavioral and Functional Task Development, Implementation, and Testing

Launched by NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM (NIAAA) · Apr 8, 2014

Keywords

ClinConnect Summary

This clinical trial is studying how alcohol use disorders affect people's behavior and brain activity. Researchers want to develop simple tasks that can be done while a person is inside a special machine called an MRI scanner. This machine takes pictures of the brain and helps scientists understand more about how alcohol impacts behavior, which can be useful for future studies.

To participate, you must be a right-handed adult between 18 and 65 years old and in good physical health. If you’re currently in a hospital for another study, you may also be eligible. Participants will go through some health checks and answer questions about their alcohol use. During the study, you will complete a computerized task, either inside the MRI scanner for about an hour, where you might need to stay still for some time, or outside of it. The scanner makes loud noises, but you'll be provided with earplugs. Please note that certain conditions, like having metal objects in your body or being pregnant, may prevent you from participating.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• • between 18-65 years of age.
• EXCLUSION CRITERIA:
• • Are not cleared on a neuromotor examination
• • Are currently receiving psychotropic medication
• • Inpatients only: Currently experiencing symptoms of withdrawal from alcohol (As determined by the most recent measurement within the
• • past 30 days CIWA score \> 8).
• -MRI Exclusion Criteria:
• • Presence of ferromagnetic objects in the body including implanted pacemakers, medication pumps, aneurysm clips, metallic prostheses (including metal pins and rods, heart valves or cochlear implants), shrapnel fragments, permanent eye liner or small metallic fragments in the eye that welders and other metal workers may have;
• • Are pregnant, as determined by a negative pregnancy test
• • Left handed
• • Claustrophobia.