Quebec Registry for Atypical Femur Fractures

Launched by MCGILL UNIVERSITY · May 27, 2014

Keywords

ClinConnect Summary

The Quebec Registry for Atypical Femur Fractures is a clinical trial that aims to better understand a specific type of bone break known as atypical femur fractures (AFF). These fractures can occur without a significant injury, often in people taking medications called bisphosphonates, which are usually prescribed to help prevent fractures in those with osteoporosis. The study will examine various factors, such as the shape and strength of the thigh bone (femur), to see if certain characteristics could predict who might be at risk for these rare fractures.

To participate in this trial, individuals must be 45 years or older and have experienced an atypical femur fracture. This includes both complete and incomplete fractures, as defined by expert guidelines. Participants will undergo 3D imaging scans to help researchers analyze the structure of their bones. The study is currently looking for volunteers from Quebec, and it’s essential to note that individuals with certain conditions, like active cancer or severe bone disorders, may not be eligible to join. Overall, this research hopes to improve our understanding of these fractures and how they can be prevented.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • age 45 years and older
• • men and women from Quebec who sustain (or have sustained) an AFF (complete or incomplete), as defined by the American Society of Bone and mineral Research (ASBMR) International Task Force on AFFs (Shane E et al J Bone Miner Res 2014;29:1-24)
• Exclusion Criteria:
• • inability to consent
• • disorders of bone metabolism other than osteoporosis
• • active cancer
• • life expectancy less than 12 months.