Laparoscopic Versus Open PANP-TME for Male Mid-low Rectal Cancer Patients

Launched by THIRD AFFILIATED HOSPITAL, SUN YAT-SEN UNIVERSITY · Jun 12, 2014

Keywords

ClinConnect Summary

No description provided

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Age from over 20 to under 60 years;
• • Primary rectal adenocarcinoma confirmed pathologically by endoscopic biopsy;
• • Mid-low rectal cancer (distance from anal edge≤12cm);
• • cT1-3, N0-3, M0 at preoperative evaluation according to the AJCC Cancer Staging Manual Seventh Edition;
• • Expected curative resection through both L-PANP-TME and O-PANP-TME;
• • Performance status of 0 or 1 on ECOG (Eastern Cooperative Oncology Group) scale;
• • ASA (American Society of Anesthesiology) score class I, II, or III;
• • Written informed consent;
• • Urinary and sexual function normal preoperatively
• Exclusion Criteria:
• • Women during pregnancy or breast-feeding;
• • Severe mental disorder;
• • History of previous pelvic surgery;
• • Enlarged or bulky regional lymph node diameter over 3cm by preoperative imaging;
• • History of other malignant disease within past five years;
• • History of unstable angina or myocardial infarction within past six months;
• • History of cerebrovascular accident within past six months;
• • History of continuous systematic administration of corticosteroids within one month;
• • Contraindication of heart, brain, lung, etc dysfunction;
• • Requirement of simultaneous surgery for other disease;
• • Emergency surgery due to complication (bleeding, obstruction or perforation) caused by rectal cancer;
• • Rectal cancer invades surrounding tissues;
• • Existence of genuine incontinence or severe stress incontinence preoperatively