ClinConnect ClinConnect Logo
Search / Trial NCT02175459

Investigating Predictive Factors of Diabetes Occurence After Duodenalpancreatectomy

Launched by FONDAZIONE POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI IRCCS · Jun 25, 2014

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Beta Cell Function Islet Cell Crosstalk Incretin Intraislet System Biomarkers Mi Rna Nc Rna Pancreatic Exocrine Endocrine Crosstalk Diabetes Of Exocrine Pancreas

ClinConnect Summary

This clinical trial is looking at how the pancreas responds after a surgery called duodenal pancreatectomy, which involves removing part of the pancreas. The main goal is to understand what factors might predict whether a person will develop diabetes after this surgery. Researchers will study individuals before and after their surgery to see how their bodies manage blood sugar levels and how the remaining pancreatic cells work to produce insulin—the hormone that helps control blood sugar.

To be eligible for the trial, participants need to be scheduled for this surgery and can either have diabetes or not. However, those with chronic diseases or who are on steroid therapy cannot take part. During the study, participants will undergo several tests to evaluate their blood sugar levels and how well their pancreas is functioning. They will also provide samples of their pancreas for further analysis. Overall, this research aims to discover important factors that help the pancreas adapt after surgery, which could lead to better management of diabetes in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • SCHEDULED FOR PANCREATECTOMY
  • NO DIABETIC and DIABETIC
  • Exclusion Criteria:
  • CHRONIC DESEASES
  • STEROID THERAPY

About Fondazione Policlinico Universitario Agostino Gemelli Irccs

Fondazione Policlinico Universitario Agostino Gemelli IRCCS is a leading research and healthcare institution based in Rome, Italy, renowned for its commitment to advancing medical science and improving patient care. As a prominent academic medical center affiliated with the Catholic University of the Sacred Heart, it integrates clinical practice, education, and research, fostering innovation in various fields of medicine. The foundation conducts a wide range of clinical trials aimed at developing new therapies and enhancing treatment protocols, with a focus on translational research that bridges the gap between laboratory discoveries and patient care. Its multidisciplinary approach and dedication to high ethical standards position it as a key player in the landscape of clinical research and healthcare improvement in Italy and beyond.

Locations

Rome, Rm, Italy

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials