SC2i Tissue and Data Repository Protocol

Launched by HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE · Jul 7, 2014

Keywords

ClinConnect Summary

This clinical trial is focused on collecting different types of body samples—like blood, urine, fluid around the brain and spine, and tissue from wounds—from people who are seriously injured or very ill. The goal is to use these samples to help develop better tests and tools that doctors can use to decide on the best treatment for both military personnel and civilians facing critical health problems. The study is currently looking for participants.

People who might be eligible include those who have injuries or illnesses that need surgery or care in emergency or intensive care settings at certain hospitals, as well as healthy volunteers and people who have recovered from past injuries. Participants will be asked to give permission for their samples to be collected and used for research. For patients who cannot give consent themselves, a family member or legal representative can do so. The study will carefully consider safety, so anyone with conditions that make giving samples risky may not be able to join. Overall, this study aims to help improve care for seriously ill or injured people by learning more from the samples collected.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with injury or illness requiring surgical care or treatment in a critical care or emergency setting who are being cared for at SC2I sites (Grady Memorial Hospital, Emory Univeristy Hospital, and Duke University Health Systems)
• • Healthy volunteer control subjects to include individuals without any known injury or end-stage organ disease and patients who have recovered from prior injury.
• • Ability to understand the purposes and risks of the study and willingly give written informed consent, or in the case of incapacitated patients, a willing surrogate able to give written informed consent.
• Exclusion Criteria:
• • Any condition that, in the opinion of the attending physician, would place the patient or volunteer subject at undue risk by participating. Specific conditions include but are not limited to anemia prohibitive of phlebotomy, coagulopathy, or technical considerations that would prevent acquisition of sufficient tissue or fluid for clinical use. Acquisition of samples from patients requiring active transfusion or with transfusion-associated coagulopathy will be considered as appropriate study candidates at the discretion of the attending physician.