Efficacy and Safety Study of Total Glucosides of Paeony Combined With Acitretin to Treat Psoriasis

Launched by XIJING HOSPITAL · Jul 11, 2014

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

• • Inclusion Criteria:Meet the following conditions
• • 1. Diagnosed according to Classification criteria for Psoriasis vulgaris;
• • 2. Patients aged 18 to 65 years (to the date of screening);
• • 3. PASI grade\>7point\<20 point;
• • 4. Not treatment in the Topical corticosteroids、Immunosuppresso、Biologicals agents or Tretinoin cream、Phototherapy nearly one months before enrolled.
• • 5. Understanding the whole process of the study, voluntary participation and signed the informed consent;
• • 6. Patient compliance is good, can guarantee in course of observation.
• Exclusion Criteria:One of the following is not included in this study:
• • 1. Pregnant women, ready to pregnant or lactating women;
• • 2. Known to root of herbaceous peony total glycosides (TGP) drug allergy;
• • 3. Have a serious heart, lung, kidney and other vital organs and endocrine system lesions and the history
• • 4. Patients is liver function abnormal persons (ALT above the center laboratory normal limit) or hepatitis b patient grain carriers;
• • 5. Need insulin control of diabetes; High blood pressure did not get good controller ;
• • 6. Patients with white blood cells \<4.0 × 109 / L, or a definite anemia (hemoglobin less than 100g / L), or platelets \<100 × 109 / L, or other blood disease;
• • 7. Patients with chronic diarrhea, or peptic ulcer nearly 1 year;
• • 8. Patients suffering from malignant tumor;
• • 9. Patients suffering from acute and chronic infectious diseases;
• • 10. Mental disorders, history of alcohol abuse, drug or other substance abuse; 11. Other cases which researchers believe that can not enroll.