Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)

Launched by OHIO STATE UNIVERSITY · Aug 29, 2014

Keywords

ClinConnect Summary

Potential study participants will be identified one of two ways, either by the treating physician in clinic when the decision is made to pursue surgery or by researchers monitoring the OR schedule. When a potential participant is identified by the treating physician in clinic, they will ask the patient if study personnel may call them to discuss the study. If the patient agrees to be contacted, the surgeon will alert study personnel who will call the patient to explain the study and arrange the initial study (screening) visit. Study personnel will monitor the OR schedule and call any potent...

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • 1. 60 years of age or older
• • 2. Capable and willing to consent
• • 3. Non-cardiac/non-neurological surgery with expected hospital stay of at least 72 H
• • 4. American Society of Anesthesiologists (ASA) physical status I-IV
• • 5. English speaking
• • 6. Willingness to use a provided tablet device
• • 7. Willingness to commit at least 1 hour per day to experimental intervention (cognitive activity/exercise) to complete a minimum of 10 hours within at least 8 days prior to surgery.
• • Exclusion criteria
• • 1. Severe visual or auditory deficits
• • 2. Illiterate
• • 3. Surgery within the previous 6 months requiring general anesthesia
• • 4. Score \< 26 on initial Mini Mental Status Exam (MMSE - modified version) (24 for patients with less than high school education)
• • 5. Positive pre-surgery Confusion Assessment Method test (CAM)
• • 6. Active depression as indicated by Geriatric Depression Scale screening test (score ≥ 10)
• • 7. History of Axis I or II psychiatric disorders including bipolar disorder, schizophrenia, dementia, alcohol or drug abuse
• • 8. ASA physical status V, VI
• • 9. Planned postoperative intubation