Effect of Mechanical Insufflation-exsufflation on Respiratory Parameters in Two Neuromuscular Populations.
Launched by CENTRE D'INVESTIGATION CLINIQUE ET TECHNOLOGIQUE 805 · Sep 8, 2014
Trial Information
Current as of July 04, 2025
Completed
Keywords
ClinConnect Summary
30 SMA and DMD adult patients will be recruited in the home ventilation unit of the intensive care department of Raymond Poincaré Hospital (Assistance Publique-Hôpitaux de Paris,Garches, France).
Respiratory parameters and comfort will be evaluated before and after (5min,
1h, 3h) a MI-E session. Vital capacity, maximal inspiratory and expiratory pressures (PImax and PEmax), peak cough flow and peak expiratory flows will be measured. Breathing pattern will be recorded allowing the measurements of respiratory frequency, tidal volume, Inspiratory time (Ti),total breath (Ttot) during tidal br...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Adults aged more than 18 years
- • Written consents
- • Neuromuscular disorders
- • Hemodynamic stability
- Exclusion Criteria:
- • Pulmonary disorder
- • Acute respiratory failure
- • Cognitive deficit
About Centre D'investigation Clinique Et Technologique 805
Centre d'Investigation Clinique et Technologique 805 is a leading research institution dedicated to advancing medical science through innovative clinical trials and technological development. With a focus on enhancing patient care and treatment outcomes, the center collaborates with healthcare professionals, academic institutions, and industry partners to conduct rigorous and ethically sound clinical research. By leveraging state-of-the-art facilities and a multidisciplinary team of experts, Centre 805 is committed to accelerating the translation of research findings into clinical practice, ultimately contributing to the betterment of public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Garches, , France
Patients applied
Trial Officials
Frederic LOFASO, MD PHD
Principal Investigator
Raymond poincare hospital
Michel Petitjean, MDPHD
Principal Investigator
Raymond Poincare hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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