OCT Angiography in Wet AMD

Launched by OREGON HEALTH AND SCIENCE UNIVERSITY · Sep 26, 2014

Keywords

ClinConnect Summary

This clinical trial is studying a new way to look at blood vessels in the eyes using a technique called optical coherence tomography (OCT) angiography. This method helps doctors see if there are new blood vessels forming in patients with wet age-related macular degeneration (AMD), a condition that can cause vision loss. The trial aims to diagnose this condition, assess how well treatments are working, and understand if reduced blood flow might increase the risk of developing wet AMD.

Adults aged 50 and older who have never been treated for wet AMD and show signs of new blood vessel growth may be eligible to participate. Additionally, adults with healthy eyes who meet certain vision criteria can also join. Participants will undergo imaging tests, which are non-invasive and painless, to help gather important information about their eyes. If you are interested in participating, it’s good to know that the study is currently recruiting and open to all genders within the specified age range.

Gender

ALL

Eligibility criteria

• Inclusion Criteria (Groups with wet AMD):
• • Adults aged 50 and older with clinical findings of treatment-naïve (never treated) neovascular AMD with active new blood vessel growth confirmed by clinical testing will be considered
• • Inclusion Criteria (Group with healthy eyes)
• • No evidence of retinal disease
• • Refractive error greater than +3.00 diopters or -7.00 diopters (glasses Rx)
• • No recent eye surgery in the last 4 months
• • No significant cataract to interfere with the quality of the imaging
• Exclusion Criteria (All Groups):
• • Inability to give informed consent
• • Significant kidney disease
• • Blood pressure greater than 180/110
• • Previous macular laser treatment
• • Inability to maintain stable fixation during OCT imaging
• • Visual acuity worse than 20/200