Gamma Knife Radiosurgery for Treatment of Essential Tremor
Launched by SWEDISH MEDICAL CENTER · Sep 30, 2014
Trial Information
Current as of August 19, 2025
Unknown status
Keywords
ClinConnect Summary
This research is being done because although multiple studies evaluating gamma knife for essential tremor show good results, few studies evaluating patients prospectively have been done. Prior studies have looked at patient outcomes following treatment - also known as retrospective studies. In this study, data collection will initiate before treatment, to obtain consistent baseline evaluations from all study participants undergoing the gamma knife treatment and at specific intervals following treatment.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Men and women age 18 years or older
- • Diagnosis of essential tremor as confirmed from clinical history and examination by a neurologist or neurosurgeon
- • Tremor following prior first line therapy with either propranolol or primidone
- • Must be able to undergo MRI of brain and CT of head for treatment planning
- • Postural or intention tremor severity score of greater than or equal to 2 in one hand/arm as measured by the CRST rating scale
- Exclusion Criteria:
- • Prior ipsilateral stereotactic radiosurgical ablation of the thalamus, ipsilateral deep brain stimulation, radiofrequency ablation of a ipsilateral thalamic target, or ultrasound ablation of an ipsilateral thalamic target
- • Prior whole brain radiation therapy
- • Pregnancy
About Swedish Medical Center
Swedish Medical Center is a leading healthcare institution renowned for its commitment to advancing medical research and improving patient care through clinical trials. With a focus on innovation and evidence-based practices, Swedish Medical Center collaborates with a diverse range of stakeholders, including academic institutions and pharmaceutical companies, to conduct rigorous clinical research across various therapeutic areas. The center prioritizes patient safety and ethical standards, ensuring that all trials are designed to enhance treatment outcomes while contributing to the broader medical community's knowledge. By fostering a collaborative environment, Swedish Medical Center aims to translate research findings into actionable clinical practices, ultimately benefiting the patients it serves.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Seattle, Washington, United States
Patients applied
Trial Officials
Christopher Loiselle, MD
Principal Investigator
Swedish Medical Center Radiosurgery Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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