Anesthetic Premedication With a Cannabis Extract (Cannapremed)

Launched by HADASSAH MEDICAL ORGANIZATION · Nov 4, 2014

Keywords

ClinConnect Summary

This clinical trial, called Cannapremed, is studying the effects of a cannabis extract on patients undergoing elective surgeries. The researchers want to see if using cannabis before surgery can help manage pain, reduce anxiety, and prevent nausea after the operation. They believe that the combination of two compounds in cannabis—THC, which can make you feel high, and CBD, which has calming effects—might provide benefits while minimizing side effects like excessive sedation or anxiety.

To participate in the trial, patients should be between the ages of 18 and 75 and scheduled for certain types of elective surgeries where they will be able to use a special pain management method called intravenous morphine patient-controlled analgesia. However, people with certain health conditions, those who have used cannabis recently, or those who are pregnant cannot join. Participants can expect to receive either the cannabis extract or standard care, and the trial is designed to carefully monitor their experiences and outcomes to see if cannabis can be a helpful option for managing pain and discomfort during recovery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients scheduled for elective surgeries suitable for postoperative pain treatment with intravenous morphine patient-controlled analgesia.
• • American Society of Anesthesiologist (ASA) risk I or II
• Exclusion Criteria:
• • ASA III or higher
• • Cannabis use within the last 6 months
• • Pregnancy
• • Emergency surgeries
• • Regional anesthesia
• • Ischemic heart disease
• • Renal failure
• • History of psychosis
• • Cognitive impairment or inability to answer questions