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Search / Trial NCT02286908

Global Strain and Mechanical Dispersion May Predict Death and Ventricular Arrhythmias Better Than Ejection Fraction

Launched by OSLO UNIVERSITY HOSPITAL · Nov 5, 2014

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

Ejection Fraction, Global Strain, Mechanical Dispersion

ClinConnect Summary

This clinical trial is studying whether certain heart measurements, called global strain and mechanical dispersion, can better predict serious heart events, like death and dangerous heart rhythms, compared to the traditional measurement known as ejection fraction (EF). The study is focused on patients who have experienced a heart attack and have heart failure, regardless of the cause. Researchers believe that these new measurements might provide more accurate information about a patient's heart health.

To participate in this trial, you should be an adult over 18 years old who has had a heart attack and is showing signs of heart failure. You also need to be scheduled to receive a special device called an implantable cardioverter-defibrillator (ICD) to help prevent life-threatening heart rhythms. If you join, you will help researchers learn more about heart health and may contribute to better treatments for others in the future. The trial is currently recruiting participants, and your involvement could make a significant difference in understanding how to care for patients with heart issues.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • All patients with
  • 1. myocardial infarction
  • 2. heart failure( defined as heart failure symptoms: reduced left ventricular function/ and or heart failure signs on chest x ray.
  • 3. planned for primary prophylactic ICD
  • over 18 years of age
  • Informed consent
  • Exclusion Criteria:
  • -

About Oslo University Hospital

Oslo University Hospital is a leading academic medical center in Norway, renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, the hospital integrates cutting-edge scientific inquiry with patient care, fostering an environment that promotes the development of new therapies and treatment strategies. With a multidisciplinary approach, Oslo University Hospital collaborates with various stakeholders, including researchers, healthcare professionals, and industry partners, to enhance clinical outcomes and contribute to the global medical community. Its dedication to ethical standards and patient safety ensures that all trials are conducted with the highest level of integrity and respect for participant welfare.

Locations

Skien, , Norway

Oslo, , Norway

Kristiansand, , Norway

Prague, , Czechia

Arendal, Agder, Norway

Drammen, , Norway

Stavanger, , Norway

Tromsø, , Norway

Trondheim, , Norway

Arendal, Agder, Norway

Patients applied

0 patients applied

Trial Officials

Thor Edvardsen, MD, PHD

Study Director

Oslo University Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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