Comparing the Efficacy of Tiotropium + Olodaterol (5/5 µg) Fixed Dose Combination (FDC) Over Tiotropium 5µg in Reducing Moderate to Severe Exacerbations in Patients With Severe to Very Severe Chronic Obstructive Pulmonary Disease.
Launched by BOEHRINGER INGELHEIM · Nov 19, 2014
Trial Information
Current as of August 28, 2025
Completed
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion criteria:
- • Male or female patients, 40 years of age or older.
- • Diagnosis of COPD with a documented post-bronchodilator Forced expiratory volume in one second (FEV1)\< 60% of predicted normal and a post-bronchodilator FEV1/ forced vital capacity (FVC) \<70% at Visit 1
- • Documented history of at least one moderate to severe COPD exacerbation in the previous 12 months requiring treatment with systemic corticosteroids and/or antibiotics and/or related hospitalization.
- • Symptomatically stable as defined by: no evidence of COPD exacerbation requiring use of either antibiotics and/or steroids 4 weeks prior to visit 1 and no evidence of change in their usual COPD medication 4 weeks prior to visit 1.
- • Current or ex-smokers with a smoking history of more than 10 pack years.
- Exclusion criteria:
- • Significant disease other than COPD.
- • Clinically relevant abnormal baseline haematology, blood chemistry or creatinine \> x2 ULN will be excluded regardless of clinical condition. ( A repeat laboratory evaluation can be conducted if deemed necessary by the investigator.)
- • Current documented diagnosis of asthma. For patients with allergic rhinitis or atopy, source documentation is required to verify that the patient does not have asthma
- • A diagnosis of thyrotoxicosis
- • A history of myocardial infarction within 6 months of screening visit.
- • Life-threatening cardiac arrhythmia.
- • Known active tuberculosis.
- • Any malignancy unless free of disease for at least 5 years (patients with treated basal cell carcinoma or squamous cell skin cancers are allowed).
- • A history of cystic fibrosis.
- • Clinically relevant bronchiectasis.
- • Patients with severe emphysema requiring endobronchial interventions within 6 months prior to screening
- • A history of significant alcohol or drug abuse in the opinion of the investigator.
- • Patients who have undergone thoracotomy with pulmonary resection
- • Patients being treated with oral or patch ß-adrenergics.
- • Patients being treated with oral corticosteroid medication at unstable doses
- • Patients being treated with antibiotics for any reasons within 4 weeks of screening visit
- • Patients being treated with PDE4 inhibitors within 3 months of screening visit
- • Patients who have taken an investigational drug within one month or six half-lives
- • Pregnant or nursing women.
- • Women of childbearing potential not using a highly effective method of birth control.
About Boehringer Ingelheim
Boehringer Ingelheim is a global, research-driven pharmaceutical company dedicated to improving health and quality of life through innovative therapies. Established in 1885 and headquartered in Ingelheim, Germany, the company focuses on the development of prescription medicines in key therapeutic areas, including respiratory diseases, cardiovascular health, oncology, and immunology. Boehringer Ingelheim is committed to advancing medical science through rigorous clinical trials and collaborative research, striving to bring novel treatments to patients while upholding the highest standards of safety and efficacy. With a strong emphasis on sustainability and corporate responsibility, the company aims to make a meaningful impact on global health challenges.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Nagasaki, Isahaya, , Japan
Kiev, , Ukraine
Tokyo, Hachioji, , Japan
Ruse, , Bulgaria
Sofia, , Bulgaria
Sofia, , Bulgaria
Sofia, , Bulgaria
Niigata, Niigata, , Japan
Niigata, Niigata, , Japan
Malaga, , Spain
Sevilla, , Spain
Ankara, , Turkey
Ankara, , Turkey
Izmir, , Turkey
Izmir, , Turkey
Ho Chi Minh, , Vietnam
Kløfta, , Norway
River Forest, Illinois, United States
North Dartmouth, Massachusetts, United States
Toledo, Ohio, United States
Philadelphia, Pennsylvania, United States
Mendoza, , Argentina
Saint John, New Brunswick, Canada
Quillota, , Chile
Beroun, , Czechia
Berlin, , Germany
Mannheim, , Germany
Nagpur, , India
Fukuoka, Kitakyushu City, , Japan
Nagano, Matumoto, , Japan
Tokyo, Chuo Ku, , Japan
Ekaterinburg, , Russian Federation
Sremska Kamenica, , Serbia
Muncie, Indiana, United States
Skierniewice, , Poland
Valencia, , Spain
Ankara, , Turkey
Kiev, , Ukraine
Pittsburgh, Pennsylvania, United States
Osaka, Osaka, , Japan
Ascona, , Switzerland
Kemerovo, , Russian Federation
Rajathevee, , Thailand
Antalya, , Turkey
Bursa, , Turkey
Bedford, , United Kingdom
Birmingham, , United Kingdom
Worcester, Massachusetts, United States
Corsicana, Texas, United States
O'fallon, Illinois, United States
Shizuoka, Hamamatsu, , Japan
Shizuoka, Shizuoka, , Japan
Poznan, , Poland
Singapore, , Singapore
Miyagi, Sendai, , Japan
New Orleans, Louisiana, United States
Coimbatore, , India
Poprad, , Slovakia
Cape Town, , South Africa
Ankara, , Turkey
Cape Town, , South Africa
Mie, Matsusaka, , Japan
Kragujevac, , Serbia
Karamsad, , India
Winnipeg, Manitoba, Canada
Wheat Ridge, Colorado, United States
Bratislava, , Slovakia
Norwalk, Connecticut, United States
Vancouver, British Columbia, Canada
New Taipei City, , Taiwan
L'hospitalet Llobregat (Bcn), , Spain
Hyderabad, , India
Cesky Krumlov, , Czechia
Nagpur, , India
Rheine, , Germany
Paderborn, , Germany
Kyiv, , Ukraine
Ciudad De Buenos Aires, , Argentina
Poway, California, United States
Ciudad De Buenos Aires, , Argentina
Tulsa, Oklahoma, United States
Shelby, North Carolina, United States
Clearwater, Florida, United States
Swidnik, , Poland
Mar Del Plata, , Argentina
Pittsburgh, Pennsylvania, United States
Johnston, Rhode Island, United States
Lincoln, California, United States
Gaffney, South Carolina, United States
Iwate, Morioka, , Japan
Vidin, , Bulgaria
Poznan, , Poland
Florence, Alabama, United States
Lafayette, Colorado, United States
Greenville, South Carolina, United States
Clearwater, Florida, United States
Tampa, Florida, United States
Burlington, North Carolina, United States
Columbus, Ohio, United States
Mount Pleasant, South Carolina, United States
Union, South Carolina, United States
Tacoma, Washington, United States
Capital Federal, , Argentina
La Plata, , Argentina
Fort Mitchell, Kentucky, United States
San Miguel De Tucuman, , Argentina
Cairns, Queensland, Australia
Graz, , Austria
Leoben, , Austria
Gilly, , Belgium
Daw Park, South Australia, Australia
Porto Alegre, , Brazil
Vitoria, , Brazil
Varna, , Bulgaria
Vancouver, British Columbia, Canada
Corunna, Ontario, Canada
Jambes, , Belgium
Victoriaville, Quebec, Canada
Jindrichuv Hradec, , Czechia
Windsor, Ontario, Canada
Turku, , Finland
Nantes Cedex 01, , France
Saint Laurent Du Var, , France
Varnsdorf, , Czechia
Augsburg, , Germany
Bad Wörishofen, , Germany
Ahlen, , Germany
Fulda, , Germany
Berlin, , Germany
Berlin, , Germany
Berlin, , Germany
Fürstenwalde, , Germany
Lübeck, , Germany
Heidelberg, , Germany
Höchstädt, , Germany
Hong Kong, , Hong Kong
Potsdam, , Germany
Radebeul, , Germany
Budapest, , Hungary
Szeged, , Hungary
Ahmedabad, , India
Jaipur, , India
Jaipur, , India
Mysore, , India
Debrecen, , Hungary
Milano, , Italy
Monza, , Italy
Palermo, , Italy
Panjim, , India
Pisa, , Italy
Parma, , Italy
Aichi, Komaki, , Japan
Pordenone, , Italy
Roma, , Italy
Fukuoka, Yanagawa, , Japan
Ibaraki, Hitachinaka, , Japan
Hokkaido, Sapporo, , Japan
Kanagawa, Kawasaki, , Japan
Hokkaido, Sapporo, , Japan
Osaka, Ikeda, , Japan
Okayama, , Japan
Osaka, Osaka, , Japan
Osaka, Yao, , Japan
Saitama, Koshigaya, , Japan
Tokyo, Itabashi Ku, , Japan
Daugavpils, , Latvia
Capital Federal, , Argentina
Fukuoka, Yukuhashi, , Japan
Fukushima, Fukushima, , Japan
Kanagawa, Kawasaki, , Japan
Harderwijk, , Netherlands
Kuala Lumpur, , Malaysia
Novosibirsk, , Russian Federation
Rostov Na Donu, , Russian Federation
Krakow, , Poland
St. Petersburg, , Russian Federation
St. Petersburg, , Russian Federation
St. Petersburg, , Russian Federation
Kosice, , Slovakia
Vrable, , Slovakia
Cape Town, , South Africa
Sombor, , Serbia
Cape Town, , South Africa
Girona, , Spain
Mérida, , Spain
Palma De Mallorca, , Spain
Liestal, , Switzerland
Singapore, , Singapore
Taipei City, , Taiwan
Kaohsiung City, , Taiwan
Denizli, , Turkey
Istanbul, , Turkey
Kyiv, , Ukraine
Ho Chi Minh, , Vietnam
Izmir, , Turkey
Ivano Frankivsk, , Ukraine
Großhansdorf, , Germany
Omsk, , Russian Federation
Chelyabinsk, , Russian Federation
Zutphen, , Netherlands
Yamanashi, Kofu, , Japan
Los Angeles, California, United States
Libiaz, , Poland
Huntersville, North Carolina, United States
Pavia, , Italy
Rapid City, South Dakota, United States
Krakow, , Poland
Vancouver, British Columbia, Canada
Monterrey, , Mexico
Oslo, , Norway
Saint Pierre La Réunion, , France
Lebbeke, , Belgium
León, , Mexico
St. Petersburg, , Russian Federation
Kettering, Ohio, United States
Santo Andre, , Brazil
Aichi, Obu, , Japan
Sittard Geleen, , Netherlands
Wroclaw, , Poland
Hoorn, , Netherlands
Elizabeth City, North Carolina, United States
Gunma, Fujioka, , Japan
Tokyo,, , Japan
Teuchern, , Germany
Bamberg, , Germany
Hyderabad, , India
Gunma, Maebashi, , Japan
Kagawa, Takamatsu, , Japan
Capital Federal, , Argentina
Kuala Terengganu, , Malaysia
Novosibirsk, , Russian Federation
St. Petersburg, , Russian Federation
Nara, Ikoma, , Japan
Osaka, Osaka, , Japan
Aichi, Seto, , Japan
Rüdersdorf, , Germany
Solingen, , Germany
Gifu, Ogaki, , Japan
Shreveport, Louisiana, United States
Osaka, Osaka, , Japan
Kent Town, South Australia, Australia
Indian Land, South Carolina, United States
Hokkaido, Sapporo, , Japan
Kiel, , Germany
Andalusia, Alabama, United States
Medford, Oregon, United States
Greenville, South Carolina, United States
Troyan, , Bulgaria
Everett, Washington, United States
Guatemala, , Guatemala
Aarhus, , Denmark
Hokkaido, Sapporo, , Japan
Kagawa, Sakaide, , Japan
Tokyo, Shinjuku Ku, , Japan
Davao City, , Philippines
Seoul, , Korea, Republic Of
Pamplona, , Spain
Spokane, Washington, United States
Wolomin, , Poland
Wilmington, North Carolina, United States
Debrecen, , Hungary
Montreal, Quebec, Canada
Kemerovo, , Russian Federation
Mersin, , Turkey
St. Petersburg, , Russian Federation
Göteborg, , Sweden
Philadelphia, Pennsylvania, United States
Leipzig, , Germany
Stamford, Connecticut, United States
Hyderabad, , India
Okinawa, Urasoe, , Japan
Taipei, , Taiwan
Istanbul, , Turkey
Topeka, Kansas, United States
Tokyo, , Japan
Osaka, Sakai, , Japan
Bucheon, , Korea, Republic Of
Hamilton, Ontario, Canada
Cincinnati, Ohio, United States
Sabadell, , Spain
Fall River, Massachusetts, United States
Birmingham, Alabama, United States
Saint Louis, Missouri, United States
Erie, Pennsylvania, United States
Rock Hill, South Carolina, United States
Killeen, Texas, United States
Kingwood, Texas, United States
Richmond, Virginia, United States
Cincinnati, Ohio, United States
Box Hill, Victoria, Australia
West Allis, Wisconsin, United States
Bahía Blanca, , Argentina
Maple Ridge, British Columbia, Canada
Wien, , Austria
Brussels, , Belgium
Hamilton, Ontario, Canada
Waterloo, Ontario, Canada
Hradec Kralove, , Czechia
Prague 8, , Czechia
Aschaffenburg, , Germany
Berlin, , Germany
Ann Arbor, Michigan, United States
Saint Louis, Missouri, United States
Murdoch, Western Australia, Australia
Coquitlam, British Columbia, Canada
Holstebro, , Denmark
Marseille, , France
Hvidovre, , Denmark
Thessaloniki, , Greece
Peine, , Germany
Halle/Saale, , Germany
Guatemala, , Guatemala
Hong Kong, , Hong Kong
Komarom, , Hungary
Szazhalombatta, , Hungary
Ahmadabad, , India
Piacenza, , Italy
Pisa, , Italy
Aichi, Nagoya, , Japan
Fukui, Fukui, , Japan
New Delhi, , India
Ferrara, , Italy
Hokkaido, Hakodate, , Japan
Hokkaido, Hakodate, , Japan
Fukuoka, Fukuoka, , Japan
Hokkaido, Obihiro, , Japan
Hyogo, Himeji, , Japan
Hyogo, Nishinomiya, , Japan
Hokkaido, Obihiro, , Japan
Kanagawa, Sagamihara, , Japan
Kanagawa, Yokohama, , Japan
Kochi, Nankoku, , Japan
Okayama, Okayama, , Japan
Osaka, Kishiwada, , Japan
Okinawa, Uruma, , Japan
Tokyo, Chuo Ku, , Japan
Tokyo, Itabashi Ku, , Japan
Tokyo, Minato Ku, , Japan
Tokyo, Shinjuku Ku, , Japan
Tokyo, Tachikawa, , Japan
Osaka, Osakasayama, , Japan
Riga, , Latvia
Wonju, , Korea, Republic Of
Riga, , Latvia
Assen, , Netherlands
Angeles City, , Philippines
Cebu City, , Philippines
Dasmarinas, , Philippines
Iloilo, , Philippines
Bialystok, , Poland
Klaipeda, , Lithuania
Kielce, , Poland
Olsztyn, , Poland
Szczecin, , Poland
Tarnobrzeg, , Poland
Almada, , Portugal
Ivanovo, , Russian Federation
Moscow, , Russian Federation
Timisoara, , Romania
Pskov, , Russian Federation
Saratov, , Russian Federation
St. Petersburg, , Russian Federation
Moscow, , Russian Federation
St. Petersburg, , Russian Federation
Nis, , Serbia
Moscow, , Russian Federation
Humenne, , Slovakia
Aranjuez, , Spain
Barakaldo (Bilbao), , Spain
Cáceres, , Spain
Pohorje, , Slovenia
Topolsica, , Slovenia
Zaragoza, , Spain
Kyiv, , Ukraine
Kyiv, , Ukraine
Bradford, , United Kingdom
Coventry, , United Kingdom
Hamar, , Norway
Valladolid, , Spain
Vic, , Spain
Spartanburg, South Carolina, United States
Bialystok, , Poland
Mar Del Plata, , Argentina
Berazategui, , Argentina
Tucumán, , Argentina
Trois Rivieres, Quebec, Canada
Minden, , Germany
Guatemala, , Guatemala
Guatemala, , Guatemala
Hokkaido, Otaru, , Japan
Spisska Nova Ves, , Slovakia
Missoula, Montana, United States
Syracuse, New York, United States
Krnov, , Czechia
Pecs, , Hungary
Tukums, , Latvia
Dayton, Ohio, United States
Orlando, Florida, United States
Delaware, Ohio, United States
Köln, , Germany
Golnik, , Slovenia
Kyoto, Kyoto, , Japan
Lisboa, , Portugal
San Isidro, , Argentina
Oaks, Pennsylvania, United States
Frankfurt, , Germany
Hannover, , Germany
Dayton, Ohio, United States
Mar Del Plata, , Argentina
Longueuil, Quebec, Canada
Oulu, , Finland
Montpellier Cedex 5, , France
Leipzig, , Germany
Leverkusen, , Germany
Hyderabad, , India
Berlin, , Germany
Riga, , Latvia
Novosibirsk, , Russian Federation
St. Petersburg, , Russian Federation
Tamarac, Florida, United States
Warszawa, , Poland
Tokyo, Shinagawa Ku, , Japan
Spartanburg, South Carolina, United States
Frankfurt, , Germany
Larchmont, New York, United States
Bowling Green, Kentucky, United States
Serres, , Greece
Edmonton, Alberta, Canada
Seoul, , Korea, Republic Of
Myrtle Beach, South Carolina, United States
Istanbul, , Turkey
Milano, , Italy
Breda, , Netherlands
Feldbach, , Austria
Roskilde, , Denmark
Saint Petersburg, Florida, United States
Morgantown, West Virginia, United States
Abingdon, Virginia, United States
Turku, , Finland
Chiba, Kamogawa, , Japan
Tokyo, Koto Ku, , Japan
San Miguel, , Chile
Linz, , Austria
Helsinki, , Finland
Granollers (Barcelona), , Spain
Vinnytsya, , Ukraine
Jasper, Alabama, United States
Leipzig, , Germany
Calabash, North Carolina, United States
Winter Park, Florida, United States
Charlotte, North Carolina, United States
Charleston, South Carolina, United States
Duluth, Georgia, United States
Columbia, South Carolina, United States
Lynchburg, Virginia, United States
Easley, South Carolina, United States
Melbourne, Victoria, Australia
Parkville, Victoria, Australia
Calgary, Alberta, Canada
Belo Horizonte, , Brazil
Porto Alegre, , Brazil
Calgary, Alberta, Canada
Cali, , Colombia
Medellín, , Colombia
Rijeka, , Croatia
London, Ontario, Canada
Ottawa, Ontario, Canada
Vaerløse, , Denmark
Sarnia, Ontario, Canada
Strasbourg, , France
ålborg, , Denmark
Tours Cedex 9, , France
Berlin, , Germany
Bochum, , Germany
Bonn, , Germany
Witten, , Germany
Leipzig, , Germany
Athens, , Greece
Athens, , Greece
Farkasgyepu, , Hungary
Godollo, , Hungary
Leipzig, , Germany
Gurgaon, , India
Vellore, , India
Aichi, Nagoya, , Japan
Aichi, Nagoya, , Japan
Hiroshima, Kure, , Japan
Hiroshima, Kure, , Japan
Ibaraki, Inashiki Gun, , Japan
Ibaraki, Naka Gun, , Japan
Vishakhapatnam, , India
Miyagi, Sendai, , Japan
Shiga, , Japan
Shimane, Izumo, , Japan
Seoul, , Korea, Republic Of
Seoul, , Korea, Republic Of
Alkmaar, , Netherlands
Almelo, , Netherlands
Amsterdam, , Netherlands
Auckland, New Zealand, , New Zealand
Manila, , Philippines
Quezon City, , Philippines
Ishikawa, Kanazawa, , Japan
Piaseczno, , Poland
St. Petersburg, , Russian Federation
St. Petersburg, , Russian Federation
Belgrade, , Serbia
Belgrade, , Serbia
Bragadiru, , Romania
Barcelona, , Spain
Barcelona, , Spain
Härnösand, , Sweden
Bucharest, , Romania
Taipei, , Taiwan
Dusit, , Thailand
Izmir, , Turkey
Kocaeli, , Turkey
Doncaster, , United Kingdom
South Shields, , United Kingdom
Athens, , Greece
Dublin 24, , Ireland
Höllviken, , Sweden
Lund, , Sweden
Flagstaff, Arizona, United States
Gainesville, Georgia, United States
Eagle, Idaho, United States
Hokkaido, Chitose, , Japan
Miyagi, Sendai, , Japan
Edmonton, Alberta, Canada
Shimane, Izumo, , Japan
Hat Yai, , Thailand
Konya, , Turkey
Ha Noi, , Vietnam
Lawrenceville, Georgia, United States
Hickory, North Carolina, United States
Stockholm, , Sweden
Odesa, , Ukraine
Peoria, Arizona, United States
Düren, , Germany
Hajdunanas, , Hungary
Kapuvar, , Hungary
Roma, , Italy
Essen, , Germany
Quilmes, , Argentina
Kolding, , Denmark
Seoul, , Korea, Republic Of
Leipzig, , Germany
Chiba, Chiba, , Japan
Bucharest, , Romania
St. Petersburg, , Russian Federation
Kelowna, British Columbia, Canada
Bucharest, , Romania
Hokkaido, Asahikawa, , Japan
Fort Worth, Texas, United States
Wilton, , Ireland
Tijuana, , Mexico
Skedsmokorset, , Norway
Lisboa, , Portugal
Kharkiv, , Ukraine
Mckinney, Texas, United States
Chertsey, , United Kingdom
Praha, , Czechia
Gütersloh, , Germany
Jaipur, , India
Saratov, , Russian Federation
Boerne, Texas, United States
Wakayama, Hidaka Gun, , Japan
Constanta, , Romania
Saint Petersburg, Florida, United States
Farmington Hills, Michigan, United States
Brooklyn, New York, United States
Gastonia, North Carolina, United States
Volgograd, , Russian Federation
Richmond, Virginia, United States
San Antonio, Texas, United States
Kogarah, New South Wales, Australia
Guatemala, , Guatemala
Hokkaido, Sapporo, , Japan
Tokyo, Toshima Ku, , Japan
Vilnius, , Lithuania
Cape Town, , South Africa
Hønefoss, , Norway
Amadora, , Portugal
Penza, , Russian Federation
Pune, , India
Fukuoka, Koga, , Japan
Hoofddorp, , Netherlands
Kaohsiung, , Taiwan
Plovdiv, , Bulgaria
St. Petersburg, , Russian Federation
Toronto, Ontario, Canada
Braga, , Portugal
Centelles, , Spain
Maerim, , Thailand
Ulyanovsk, , Russian Federation
Berlin, , Germany
Berlin, , Germany
Perugia, , Italy
East Providence, Rhode Island, United States
Rotterdam, , Netherlands
Marlton, New Jersey, United States
Ostow Wielkopolski, , Poland
Traverse City, Michigan, United States
Fridley, Minnesota, United States
Miyagi, Sendai, , Japan
Saitama, Saitama, , Japan
Opelousas, Louisiana, United States
Pittsburgh, Pennsylvania, United States
Kanagawa, Yokohama, , Japan
Rosario, , Argentina
Campbelltown, New South Wales, Australia
Shreveport, Louisiana, United States
Randwick, New South Wales, Australia
Baltimore, Maryland, United States
Columbia, Maryland, United States
Hollywood, Maryland, United States
Salzburg, , Austria
Brussel, , Belgium
Turnhout, , Belgium
Zichem, , Belgium
Moncton, New Brunswick, Canada
Saint John¿S, Newfoundland And Labrador, Canada
Burlington, Ontario, Canada
Botucatu, , Brazil
Goiania, , Brazil
Courtice, Ontario, Canada
Grimsby, Ontario, Canada
Hamilton, Ontario, Canada
Toronto, Ontario, Canada
Point Claire, Quebec, Canada
Saskatoon, Saskatchewan, Canada
Saskatoon, Saskatchewan, Canada
Bogotá, , Colombia
Bogotá, , Colombia
Bogotá, , Colombia
Melnik, , Czechia
Odense, , Denmark
Cannes, , France
La Tronche, , France
Marseille Cedex 08, , France
Nice, , France
Nîmes Cedex 9, , France
Nîmes, , France
St Charles Borromée, Quebec, Canada
Paris, , France
Reims, , France
Rennes Cedex 9, , France
Toulouse Cedex 9, , France
Ste Foy, Quebec, Canada
Bielefeld, , Germany
Frankfurt, , Germany
Frankfurt, , Germany
Landsberg Am Lech, , Germany
Vieux Condé, , France
Kolkata, , India
Ludhiana, , India
Madurai, , India
Mysore, , India
Nagpur, , India
Mannheim, , Germany
Marburg, , Germany
Roma, , Italy
San Pietro Vernotico (Br), , Italy
Sassari, , Italy
Scafati (Sa), , Italy
Fukuoka, Kurume, , Japan
Hiroshima, Hiroshima, , Japan
Gunma, Takasaki, , Japan
Goyang, , Korea, Republic Of
Ede, , Netherlands
Gwangju, , Korea, Republic Of
Eindhoven, , Netherlands
Hamilton, , New Zealand
Groningen, , Netherlands
Tauranga, , New Zealand
Zagreb, , Croatia
Kirov, , Russian Federation
Lomonosov, , Russian Federation
Budapest, , Hungary
Edeleny, , Hungary
Taipei, , Taiwan
Nyiregyhaza, , Hungary
Pecs, , Hungary
Ahmedabad, , India
Muang, , Thailand
Seoul, , Korea, Republic Of
Muang, , Thailand
Valmiera, , Latvia
Lodz, , Poland
Kaunas, , Lithuania
Klaipeda, , Lithuania
Porto Alegre, , Brazil
Porto Alegre, , Brazil
Quebec, , Canada
Lublin, , Poland
Santiago De Chile, , Chile
Pessac, , France
Hannover, , Germany
Bergisch Gladbach, , Germany
Berlin, , Germany
Hamburg, , Germany
Ostroda, , Poland
Nafplio, , Greece
Thessaloniki, , Greece
Poznan, , Poland
Zawadzkie, , Poland
Zgierz, , Poland
Hong Kong, , Hong Kong
Bangalore, , India
Messina, , Italy
Pretoria, , South Africa
Arkhangelsk, , Russian Federation
Pretoria, , South Africa
Alicante, , Spain
Barnaul, , Russian Federation
Liencres (Pielagos), , Spain
Madrid, , Spain
Gatchina, , Russian Federation
Kazan, , Russian Federation
Hyogo, Himeji, , Japan
Coimbra, , Portugal
Bern, , Switzerland
Porto, , Portugal
Saint Charles, Missouri, United States
Guimarães, , Portugal
Vila Nova De Gaia, , Portugal
Reno, Nevada, United States
Ryazan, , Austria
Liberec, , Czechia
Wiesloch, , Germany
Heraklion, , Greece
Kota Bahru, , Malaysia
Charlotte, North Carolina, United States
Aguascalientes, , Mexico
Nagano, Matsumoto, , Japan
Leeuwarden, , Netherlands
Yamagata,, , Japan
Cittadella (Pd), , Italy
Yamaguchi, Iwakuni, , Japan
New Taipei, , Taiwan
Chermside, Queensland, Australia
Hiroshima, Fukuyama, , Japan
Zagreb, , Croatia
Guadalajara, , Mexico
México, , Mexico
Dunedin, , New Zealand
Belgrade, , Serbia
Belgrade, , Serbia
Martin, , Slovakia
Morningside, Sandton, , South Africa
Parow, , South Africa
Kaohsiung, , Taiwan
Taipei, , Taiwan
Sao Paulo, , Brazil
Lodz, , Poland
Woodville, South Australia, Australia
Osaka, Toyonaka, , Japan
Tokyo, Chiyoda Ku, , Japan
Tokyo, Meguro Ku, , Japan
München, , Germany
Amanzimtoti, , South Africa
Milano, , Italy
Padova, , Italy
Leiden, , Netherlands
Christchurch Central, , New Zealand
Gifu, Mizunami, , Japan
Hyogo, Kobe, , Japan
Christchurch, , New Zealand
Gaffney, South Carolina, United States
Kagoshima, Kagoshima, , Japan
Kanagawa, Isehara, , Japan
Kanagawa, Kawasaki, , Japan
Kanagawa, Sagamihara, , Japan
Niigata, Niigata, , Japan
Tochigi, Shimotsuke, , Japan
Saratov, , Russian Federation
Dunedin, , New Zealand
Rochester, Minnesota, United States
Moscow, , Russian Federation
Hokkaido, Sapporo, , Japan
Arendal, , Norway
Hokkaido, Sapporo, , Japan
München, , Germany
Pune, , India
Kuching, , Malaysia
Lierskogen, , Norway
Bialystok, , Poland
Hokkaido, Sapporo, , Japan
Hokkaido, Tomakomai, , Japan
Osaka, Takatsuki, , Japan
Bydgoszcz, , Poland
Chojnice, , Poland
Katowice, , Poland
Aveiro, , Portugal
Rosto On Don, , Russian Federation
Tokyo, Shinjuku Ku, , Japan
Wakayama, Wakayama, , Japan
Yamagata, Yonezawa, , Japan
Yamaguchi, Ube, , Japan
Kochi, Kochi, , Japan
Sao Paulo, , Brazil
Yaroslavl, , Russian Federation
Chesterfield, Missouri, United States
Tomsk, , Russian Federation
Greenlane East Auckland Nz, , New Zealand
Tomsk, , Russian Federation
Vilanova I La Geltrú, , Spain
São Paulo, , Brazil
Koblenz, , Germany
Wardenburg, , Germany
Kagawa, Takamatsu, , Japan
Houston, Texas, United States
Patumwan, , Thailand
Bucharest, , Romania
Badalona, , Spain
Madrid, , Spain
Pozuelo De Alarcón, , Spain
Rättvik, , Sweden
Patients applied
Trial Officials
Boehringer Ingelheim
Study Chair
Boehringer Ingelheim
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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