Long-term Outcomes of Endoscopic Resection (ER) of Lesions of the Duodenum and Ampulla

Launched by PROFESSOR MICHAEL BOURKE · Dec 2, 2014

Keywords

ClinConnect Summary

This clinical trial is studying the long-term results of a procedure called endoscopic resection, which is a way to safely remove abnormal growths (lesions) from the duodenum and ampulla, parts of the small intestine. The goal is to find out how effective and safe this method is for treating larger lesions, specifically those that are more than 10 millimeters in size and are restricted to the surface layers of the tissue.

To participate in this trial, individuals must be at least 18 years old and have a duodenal or ampullary lesion larger than 10mm that is not invading deeper layers of tissue. Those with smaller lesions or those that have spread deeper into the tissue are not eligible. If someone joins the study, they can expect to undergo the endoscopic resection procedure and will be monitored for their health outcomes over time. This research could help improve future care for patients with similar conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • \* Duodenal and ampullary lesion \> 10mm
• • Lesion limited to the mucosal and/or submucosal layer (T1 lesion)
• • Aged 18 years or older
• Exclusion Criteria:
• • Lesion less than 10mm
• • Duodenal or ampullary lesion involves the muscularis propria (T2 lesion) on other staging modalities such as endoscopic ultrasonography (EUS)
• • Aged younger than 18 years