Adaptive Optics Retinal Imaging

Launched by NATIONAL EYE INSTITUTE (NEI) · Dec 13, 2014

Keywords

ClinConnect Summary

This clinical trial is studying a new technique called adaptive optics to see if it can help doctors find eye diseases earlier and improve how they diagnose and treat these conditions. By using this advanced imaging method, researchers hope to get a clearer view of the retina, the light-sensitive tissue at the back of the eye, which is often damaged by diseases before patients even notice symptoms.

To participate, you need to be at least 12 years old and either have an eye disease or be a healthy volunteer with no significant eye problems. During the study, you'll undergo some eye exams, including having your pupils dilated and using the adaptive optics instrument to take detailed images of your retina. You may also have additional tests like color vision checks and special measurements of how your eyes respond to light. The trial is currently recruiting participants, and it's important to know that certain eye conditions or allergic reactions to specific dyes may prevent someone from joining.

Gender

ALL

Eligibility criteria

• * INCLUSION CRITERIA:
• Participants will be eligible if they:
• • Are 12 years of age or older.
• • Have the ability to cooperate with an eye exam and adaptive optics imaging.
• • Have the ability to understand and sign an informed consent or have a parent/legal guardian to do so if they are minor children.
• • Have an eye disease or are a healthy volunteer with a normal eye exam (no visually-significant eye findings on examination).
• EXCLUSION CRITERIA:
• Participants will not be eligible if:
• • -They have a condition which prevents adequate images from being obtained (e.g. unstable fixation or media opacity).
• • EXCLUSION CRITERIA FOR FLUORESCEIN AND/OR INDOCYANINE GREEN IMAGING
• Partaicipants are not eligible for fluorescein and/or indocyanine green imaging if they:
• • Are under 18 years of age.
• • For participants who will undergo fluorescein imaging have a history of adverse reaction to fluorescein.
• • For participants who will undergo indocyanine green imaging have a history of adverse reaction to indocyanine green dye, know or suspected allergies to iodine or shellfish.