Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With Anticoagulation

Launched by CEDARS-SINAI MEDICAL CENTER · Dec 12, 2014

Keywords

ClinConnect Summary

This clinical trial is looking at how well a special type of heart valve, called a bioprosthetic valve, works after it has been placed in patients. The study will use advanced imaging techniques to check the valve's condition and see if any early signs of problems, known as thrombosis (which means blood clots forming on the valve), can be treated with blood-thinning medications called anticoagulants. The main goal is to ensure these valves are functioning properly and to confirm that treatment can help resolve any issues.

To participate in this study, you need to be at least 18 years old and have had a transcatheter or surgical bioprosthetic aortic valve placed at least two days before joining. Unfortunately, if you have kidney problems or are allergic to certain contrast dyes used in imaging, you would not be eligible. If you choose to participate, you can expect regular follow-ups and tests to monitor the condition of your valve and the effectiveness of the anticoagulation treatment. This study is currently looking for participants, and it aims to provide valuable information for better managing heart valve health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Presence of transcatheter or surgical bioprosthetic aortic valve implanted at least 48 hours prior to enrollment
• • Age 18 years or older
• • Ability to provide informed consent and follow-up with protocol procedures.
• Exclusion Criteria:
• • Renal insufficiency (creatinine \> 1.5 mg/dL)
• • Known allergy to iodinated contrast agents