Inflammation and Obesity-associated Disease

Launched by GÖTEBORG UNIVERSITY · Dec 17, 2014

Keywords

ClinConnect Summary

This clinical trial is studying how inflammation and obesity are connected to various health problems such as kidney disease, liver disease, and heart-related issues. Researchers believe that when people are obese, their bodies might not produce enough special substances that help reduce inflammation, which can lead to serious health conditions. The trial will look at the levels of inflammation in fat tissue from obese individuals and how this relates to the presence of diseases associated with obesity. Additionally, the study will explore whether certain anti-inflammatory treatments can help change the way immune cells in fat tissue behave.

To participate in this trial, you need to be between the ages of 65 and 74 and have a body mass index (BMI) of 35 to 55 if you are obese, or a BMI of 18.5 to 24.9 if you are lean. Unfortunately, individuals taking certain medications like anti-inflammatory drugs or those who smoke or abuse alcohol cannot join the trial. If you decide to participate, you’ll be contributing to important research that could help improve understanding and treatment of obesity-related diseases.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Obese BMI 35-55 kg/m2
• • Lean BMI 18.5-24.9
• Exclusion Criteria:
• • Medical treatment with NSAIDs, corticosteroid treatment, immune-suppressants.
• • Other: smoking, alcohol abuse.