MSM Product on Attenuating Nasal Provocation With a Standardized Allergenic Challenge

Launched by MEDICUS RESEARCH, LLC · Jan 14, 2015

Keywords

ClinConnect Summary

Allergic rhinitis, or nasal allergy, is a common condition throughout the world which affects both adult and children alike. It is a group of symptoms characterized by red, itchy eyes, a blocked, itching, runny nose, rhinorrhea, and sneezing. Other reported symptoms include throat clearing, headaches, facial pain, ear pain, itchy throat and palate, snoring, and sleep disturbances. Nasal allergy commonly occurs when an individual's immune system reacts to allergens such as grass, weed, or tree pollens, house dust, mites, mold, and animal dander \[1, 2\].

Allergic rhinitis is considered to h...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy volunteers ≥ 18 and ≤ 65 years of age
• • Subjects with history of nasal congestion in response to pollen, dust mites, cat dander, and/or dog dander
• • Subjects who score "moderate" or "severe" on the VAS Nasal Symptom Score in response to an allergenic challenge at screening (V1)
• • Judged by the Investigator to be in general good health on the basis of medical history
• Exclusion Criteria:
• • Pregnant and/or lactating women
• • Subjects with idiopathic rhinitis, atrophic rhinitis, or rhinitis medicamentosa