Swedish Iodine in Pregnancy and Development in Children (SWIDDICH) Study

Launched by GÖTEBORG UNIVERSITY · Mar 3, 2015

Keywords

ClinConnect Summary

The SWIDDICH study is looking at whether taking a daily supplement containing iodine and other vitamins and minerals during pregnancy can help support the brain development of babies when mothers have mild iodine deficiency. Iodine is important for healthy thyroid function and brain development, especially in unborn babies. While Sweden has put measures in place to prevent severe iodine deficiency, there are concerns that some pregnant women may still have mild deficiency. The study aims to find out if this mild deficiency affects children’s cognitive development as they grow, compared to children whose mothers receive adequate iodine.

To participate in the study, pregnant women need to be between 18 and 40 years old and in their first trimester (less than 13 weeks pregnant). They should be planning for a full-term pregnancy and agree not to take any iodine supplements outside of the study. Women with known thyroid issues or those who are vegan are not eligible. Participants can expect to take the study supplement throughout their pregnancy and will have their child's cognitive development assessed at different ages after birth. This study is important because understanding the effects of mild iodine deficiency during pregnancy can help improve health outcomes for children in the future.

Gender

FEMALE

Eligibility criteria

• • PREGNANT WOMEN
• • Inclusion criteria
• • Pregnant, week \<13
• • Age 18-40 years
• • Intent of a full term pregnancy
• • Agreement of taking no iodide containing supplements during the study except for study supplement
• • Exclusion Criteria
• • Known current thyroid disease
• • Risk factors for thyroid disease (history or heredity for thyroid, other autoimmune disease or symptoms of hypo-/hyperthyroidism) where the TSH is abnormal
• • Possibility to not attend to the protocol according to the investigator's opinion
• • Less than 6 months from previous pregnancy or lactating period
• • Vegan
• • CONTROL WOMEN
• • Inclusion criteria
• • Age 18-40 years
• • Agreeing not to take iodide containing supplements 1 week prior to the collecting of the samples.
• • Exclusion criteria
• • Current thyroid disease
• • Risk factors for thyroid disease (history or heredity for thyroid or other autoimmune disease or symptoms of hypo-/hyperthyroidism) where the TSH is abnormal
• • Possibility to not attend to the protocol according to the investigator's opinion
• • Currently pregnant or lactating
• • Less than 6 months from previous pregnancy or lactating period
• • Vegans