MRI/Ultrasound Fusion Guided Prostate Cryotherapy

Launched by UROLOGICAL RESEARCH NETWORK, LLC · Mar 5, 2015

Keywords

ClinConnect Summary

This clinical trial is studying a new way to treat prostate cancer using a method called cryotherapy, which involves freezing cancer cells to destroy them. The treatment is guided by advanced imaging techniques, including MRI and ultrasound, to ensure that the cancerous areas identified by a biopsy are precisely targeted. The main goal is to see how well this treatment controls the cancer over five years while minimizing any negative effects on the patients' quality of life.

Men aged 55 to 65 with low to intermediate risk prostate cancer, or men over 65 with certain conditions, may be eligible to participate. To qualify, they should have specific characteristics such as a low percentage of positive biopsy results and no signs of advanced cancer spreading beyond the prostate. Participants in this trial can expect to receive focused treatment aimed at eradicating the cancer while being carefully monitored to ensure their overall well-being. This trial is currently recruiting participants, and it's a promising step toward better prostate cancer care.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Men between 55 and 65 years of age with a clinical diagnosis of prostate cancer with Low or Intermediate risk prostate cancer, and \<50% positive core rate by prostate lobe
• • Men older than 65 years of age with clinical diagnosis of prostate cancer \<50% positive core rate by prostate lobe
• • Absence of extra-capsular extension
• • Absence of seminal vesicle invasion
• • Absence of regional or distant metastatic disease
• • Multiparametric MRI of the prostate performed either before the biopsy or \>10 weeks after prostate biopsy
• • Treated with Cryotherapy of the prostate
• • Treatment based on co-registration between MP-MRI and Prostate Ultrasound
• Exclusion Criteria:
• • Prior treatment of prostate cancer in the form of surgery.
• • Performance status greater than 0 based on ECOG criteria
• • Mental status impairment