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Search / Trial NCT02395640

The Comparison of XELOX and EOX in the First-line Treatment of Advanced Gastric Cancer

Launched by FUDAN UNIVERSITY · Mar 17, 2015

Trial Information

Current as of June 22, 2025

Completed

Keywords

ClinConnect Summary

This study is designed to compare the efficacy and safety of XELOX regimen with EOX regimen in the first-line treatment of advanced gastric cancer patients.

Gender

ALL

Eligibility criteria

  • Major inclusion criteria
  • had a histologically proven adenocarcinoma of the gastroesophageal junction, or stomach that was locally advanced (inoperable) or metastatic
  • measurable disease, according to the Response Evaluation Criteria in Solid Tumors (RECIST)1.1
  • an Eastern Cooperative Oncology Group performance status of 0 to 2
  • adequate renal, hepatic, and hematologic function
  • Major exclusion criteria
  • previous chemotherapy or radiotherapy (unless in the adjuvant setting)
  • uncontrolled cardiac disease, or other clinically significant, uncontrolled coexisting illness or previous or concurrent cancer
  • accumulated dose of Epirubicin exceeds 300mg/m2
  • HER2 positive and willing to use trastuzumab

About Fudan University

Fudan University, a prestigious comprehensive research university located in Shanghai, China, is committed to advancing medical science through innovative clinical research. Renowned for its rigorous academic standards and cutting-edge research facilities, Fudan University plays a pivotal role in the global health landscape by sponsoring a diverse array of clinical trials aimed at improving patient outcomes and addressing pressing medical challenges. Leveraging its multidisciplinary expertise and collaborative networks, the university strives to translate scientific discoveries into practical applications, fostering advancements in healthcare and contributing to the well-being of communities both locally and internationally.

Locations

Shanghai, Shanghai, China

Shanghai, Shanghai, China

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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