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Search / Trial NCT02432079

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

Launched by INDIANA UNIVERSITY · Apr 30, 2015

Trial Information

Current as of July 09, 2025

Recruiting

Keywords

Abnormalities, Multiple Asplenia Bilary Atresia Birth Defect Cardiovascular Abnormalities Cardiovascular Diseases Congenital Abnormalities Congenital Heart Disease Dextrocardia Syndrome Disturbed Internal Organ Positioning Genetics Genetic Testing Heart Defects, Congenital Heart Diseases Heterotaxy Syndrome Intestinal Malrotation Laterality Left Atrial Isomerism Pediatrics Polysplenia Right Atrial Isomerism Splenic Diseases Cilia Situs Inversus Dextrocardia

ClinConnect Summary

This clinical trial is focused on understanding the genetic causes of heterotaxy syndrome and related congenital heart defects. Heterotaxy is a condition where the organs in the body are arranged differently than usual, which can also affect the heart. By collecting samples and information from individuals with these conditions and their families, researchers hope to learn more about how these disorders develop. This knowledge could help doctors provide better genetic counseling in the future and improve our understanding of how the body normally develops its left-right symmetry.

To participate in this study, individuals must have heterotaxy or related congenital heart defects, and family members of these individuals are also welcome to join. Unfortunately, those without these conditions or their family members cannot participate. If you decide to join the trial, you can expect to provide some biological samples and personal information that will be used to advance research in this area. This study is currently recruiting, and anyone interested should reach out to learn more about how to get involved.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Subjects with heterotaxy and related congenital heart defects
  • Family members of subjects with heterotaxy and related congenital heart defects
  • Exclusion Criteria:
  • Subjects without heterotaxy and related congenital heart defects
  • Family members of subjects without heterotaxy and related congenital heart defects

About Indiana University

Indiana University, a leading research institution, is committed to advancing healthcare through innovative clinical trials and rigorous scientific inquiry. With a focus on improving patient outcomes, the university conducts a wide range of studies across various medical disciplines, leveraging its extensive resources and collaborative networks. Indiana University's dedication to ethical research practices and community engagement ensures that its clinical trials not only contribute to scientific knowledge but also prioritize participant safety and well-being. Through its commitment to excellence, Indiana University plays a pivotal role in shaping the future of medicine and enhancing public health.

Locations

Indianapolis, Indiana, United States

Patients applied

0 patients applied

Trial Officials

Stephanie M. Ware, MD, PhD

Principal Investigator

Indiana University School of Medicine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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