Oral Immunotherapy in Cow's Milk Allergy (CMA) in Children : "Petit Lait" Study

Launched by DR FLORE AMAT · Jun 4, 2015

Keywords

ClinConnect Summary

The study prospectively included children aged older than 3 years, with an IgE-CMA.

Children were part of the " Petit Lait " Study, led from June 2012 in the Allergology Department of Armand Trousseau Children's Hospital, "Assistance Publique-Hôpitaux de Paris (AP-HP)", France

1. Inclusion criteria All the children presenting with a diagnosis of IgE- CMA(defined as a history of reaction to the ingestion of cow's milk product and positive skin prick test (wheal ≥3 mm to cow's milk with no reaction to the negative control and specific IgE to casein \>0.35 (kiloUnit) kU/l) and referred to on...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All the children presenting with a diagnosis of IgE- CMA(defined as a history of reaction to the ingestion of cow's milk product and positive skin prick test (wheal ≥3 mm to cow's milk with no reaction to the negative control and specific IgE to casein \>0.35 kU/l)
• Exclusion Criteria:
• • Children who have presented an anaphylactic reaction during the previously year, who reacted with placebo during the DBPCFC or those with lacking consent or parents having difficulties to understand the protocol