Pediatric Arm of DZL All Age Asthma Cohort

Launched by LMU KLINIKUM · Jul 9, 2015

Keywords

ClinConnect Summary

This clinical trial, called the Pediatric Arm of the DZL All Age Asthma Cohort, is focused on understanding why some children develop asthma and wheezing while others do not. Researchers want to learn more about the different types of asthma in children and how these might relate to asthma that begins in adults. By identifying the underlying causes of asthma, the goal is to create more personalized treatments that can help children manage their condition better and potentially prevent asthma from becoming a long-term issue.

To participate, children aged between 6 months and 18 years who have experienced wheezing or have a doctor-diagnosed asthma may be eligible. Parents must provide consent, and children older than 8 years will also need to agree to join the study. Participants will be asked to share their medical history and may undergo some assessments to help researchers gather important information. This study is currently recruiting and welcomes children of all genders. It's an opportunity to contribute to important research that could lead to better asthma care for children in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • informed consent by parents (and by children if age \> 8 years)
• • age 6 months to 18 years
• • term delivery (≥ 37 weeks)
• • active/passive understanding of German
• • age 6 months - \< 6 years: preschool wheeze (more than two episodes of wheeze during 12 months prior to inclusion)
• • age at least 6 years: doctor diagnosed asthma (according to current guidelines)
• Exclusion Criteria:
• • known inborn or perinatal pulmonary disease
• • airway malformation
• • oxygen therapy after birth with a duration of more than 24 hours
• • ventilator support or mechanical ventilation after birth
• • diagnoses of cystic fibrosis; primary ciliary dyskinesia
• • heart failure diagnosed after birth affecting pulmonary circulation
• • major respiratory diseases such as e.g. interstitial lung disease
• • any current non-atopic comorbidity
• • fever of at least 38.5°C during the last two weeks prior to the planned first visit