Impact of IL-28B rs12979860 and rs4803217 Gene Polymorphisms Associated With miRNAs Deregulation on HCV-related Hepatocellular Carcinoma
Launched by DR.WALEED SAMIR · Jul 22, 2015
Trial Information
Current as of July 21, 2025
Unknown status
Keywords
ClinConnect Summary
Introduction
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide. Despite improvements in HCC therapy, the prognosis for HCC patients remains poor due to a high incidence of recurrence. An improved understanding of the pathogenesis of HCC development would facilitate the development of more effective outcomes for the diagnosis and treatment of HCC at earlier stages.
Currently, molecular alterations in tumors are being scrutinized at a genome-wide scale, covering different dimensions, such as gene expression, epigenetic changes, chromosomal aberrations, and...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • HCV-infected patients confirmed by RT-PCR with and without fibrosis, cirrhosis and HCC
- Exclusion Criteria:
- • HCV/HIV co-infection
About Dr.Waleed Samir
Dr. Waleed Samir is a distinguished clinical trial sponsor dedicated to advancing medical research and improving patient outcomes through rigorous and innovative study designs. With a strong background in clinical medicine and a commitment to ethical research practices, Dr. Samir leads trials that focus on developing new therapies and interventions across various therapeutic areas. His collaborative approach involves engaging multidisciplinary teams and leveraging cutting-edge methodologies to ensure the highest standards of scientific integrity and patient safety. Through his leadership, Dr. Samir aims to contribute significantly to the body of medical knowledge and facilitate the translation of research findings into effective clinical applications.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Sherbein, Dakhlya, Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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