Insulin Dose Adjustments for Meals Differing in Fat Content in T1DM
Launched by NORTHUMBRIA UNIVERSITY · Nov 2, 2015
Trial Information
Current as of June 27, 2025
Completed
Keywords
ClinConnect Summary
Study design and Methodology General Design: 18 male or female type 1 diabetes (T1DM) individuals aged between 18 and 50 years old will be invited to attend four laboratory sessions, each separated by 7 days. Participants will be recruited in clinic and through advertising in local media. Participants will complete four main trials in a randomised and counter balanced fashion. Main trials will involve the manipulation of both the meal composition (fat content) and rapid-acting insulin dose. During each visit blood samples will be measured over a 6 hour postprandial period to determine glyca...
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • For inclusion in the study, volunteers will be -
- • either male or female and aged 18-50 years old
- • free from any diabetes complications apart from background diabetic retinopathy
- • not taking any prescribed medication other than insulin
- • treated with a stable insulin regimen composed of a combination of slow/long acting insulin glargine/determir and a fast acting insulin analogue (lispro or aspart, glulisine)
- • have a HbA1c of \<9.5% (80 mmol/mol)
- • using the carbohydrate counting method for administering meal time rapid-acting insulin.
About Northumbria University
Northumbria University is a leading research-intensive institution based in the UK, dedicated to advancing knowledge and innovation in various fields, including health sciences. As a clinical trial sponsor, the university leverages its academic expertise and state-of-the-art facilities to conduct high-quality research aimed at improving patient outcomes and informing clinical practices. With a commitment to ethical standards and regulatory compliance, Northumbria University collaborates with healthcare professionals and industry partners to explore novel therapeutic interventions and contribute to the body of evidence that shapes modern medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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