Dendritic Cells in Patients With Acute or Chronic Skin Graft Versus Host Disease

Launched by WASHINGTON UNIVERSITY SCHOOL OF MEDICINE · Nov 18, 2015

Keywords

ClinConnect Summary

This clinical trial is studying the role of special immune cells called dendritic cells (DCs) in patients who have skin graft-versus-host disease (GVHD). GVHD can happen after a bone marrow transplant when the new immune cells attack the skin, leading to various symptoms. The researchers want to understand how different types of dendritic cells in the skin contribute to the onset and progression of this condition. By learning more about these immune cells, they hope to find better ways to manage or treat skin GVHD.

To participate in this trial, you must be at least 18 years old and have been diagnosed or suspected of having either acute or chronic skin GVHD. You will also need to be able to provide consent to join the study. Unfortunately, individuals with certain infections, like hepatitis or HIV, or pregnant women cannot take part. Participants will be monitored closely throughout the study, and they will receive information about what to expect as the trial progresses. This research is important as it may lead to new treatments for patients suffering from skin GVHD.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • At least 18 years of age at enrollment
• • Willing and able to sign the informed consent
• • Current diagnosis/suspected diagnosis of acute skin GVHD OR Current diagnosis/suspected diagnosis of chronic skin GVHD
• Exclusion Criteria:
• • Known infection with Hepatitis B or C, HTLV, or HIV
• • Pregnant females