Reliability of Pupil Response to Acute Pain

Launched by WAKE FOREST UNIVERSITY HEALTH SCIENCES · Dec 8, 2015

Keywords

ClinConnect Summary

This clinical trial is studying how the size of a person's pupils responds to acute pain, specifically in individuals with arthritis in their hips or knees. When someone feels pain, their pupils can change size, and researchers want to see if these changes can reliably indicate how much pain a person is experiencing. This information could help doctors better understand pain and improve treatment options in the future.

To participate in this study, you should be an adult aged 18 to 70 who experiences moderate pain from hip or knee arthritis. You will not be eligible if you have certain medical conditions, are pregnant, or have a history of specific eye surgeries. If you join the trial, you can expect to answer some questionnaires and undergo tests to measure how your pupils respond to pain. This research is currently looking for volunteers, and all genders are welcome to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adult (18-70)
• • Pain from hip or knee arthritis of moderate intensity
• • American Society of Anesthesiologists physical status 1-3
• Exclusion Criteria:
• • Inability to complete study questionnaires
• • Pregnancy
• • Litigation or workers compensation related to hip or knee pain
• • Taking \> 50 mg morphine equivalents/day
• • History of Raynaud's disease of the feet
• • Psychotic disorder or a recent psychiatric hospitalization
• • History of eye surgery or topical eye medications that would would directly affect pupil diameter