Magnetic Seed Localisation of Breast Cancers

Launched by MANCHESTER UNIVERSITY NHS FOUNDATION TRUST · Dec 16, 2015

Keywords

ClinConnect Summary

Background and Rationale Breast Cancer Breast cancer is a heterogeneous disease, with great diversity in the site, size and progression of tumours. Some are palpable and discovered by the patient, though many are first detected during mammogram screening. For such cancers, localisation is necessary prior to surgery, to guide surgeons to the target excision site.

Wire Guided Localisation Traditionally, localisation involves radiographic-guided insertion of a wire into the breast, with positioning of the wire tip at the centre of the lesion. However, this procedure carries several logistical...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Participant is willing and able to give informed consent for participation in the study;
• • Female, aged 18 years or above;
• • Diagnosed with breast cancer (invasive or dcis);
• • Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study;
• • Undergoing mastectomy breast surgery.
• Exclusion Criteria:
• • Patients with a Pacemaker or implanted device;
• • Patients requiring an MRI scan prior to surgery;
• • Patients with known coagulopathy or receiving anticoagulant medication including warfarin, heparin, clopidogrel or rivaroxaban;
• • Patients receiving Neoadjuvant chemotherapy;
• • Patients who are pregnant or lactating;
• • Patients scheduled for immediate breast reconstruction;
• • Patients who have received Sienna (iron oxide) injection in the previous six months;
• • Patients with an existing breast haematoma close to the target lesion.