Prospective Registry of Prosthodontic Rehabilitation in Oncology Patients Undergoing Jaw Reconstruction
Launched by AZ SINT-JAN AV · Jan 19, 2016
Trial Information
Current as of July 25, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is focused on gathering information about patients with head and neck cancer who need jaw reconstruction. The goal is to create a database that tracks important details about patients, their surgeries, dental care, and quality of life over time. This study is specifically looking at patients who have certain conditions affecting their jawbone due to cancer treatment or disease, and who are eligible for special dental implants that can be placed right after their jaw is rebuilt or at a later time.
To participate in this trial, individuals of any age and gender must have a confirmed diagnosis related to their jaw and oral cavity that requires significant surgery. They should also not be suitable for traditional removable dentures. Participants can expect to visit the clinic regularly, where their progress and experiences will be recorded to help improve future treatments for similar patients. It's important to know that this study is currently recruiting participants, and it aims to enhance the understanding of how to better support patients undergoing these complex procedures.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients of all ages
- • Patients of all genders
- • Patients with a histologically or clinically confirmed diagnosis of ORN, MRONJ, as classified by Ruggiero et al. (Ruggiero, et al., 2014) or carcinoma located in the oral cavity and jawbone, requiring segmental or total jaw resection
- • Patients eligible for jaw and oral cavity reconstruction combined with immediate/delayed implant loading for fixed prosthetic rehabilitation
- • Patients not eligible for conventional removable prosthetic rehabilitation
- Exclusion Criteria:
- • Patients with a clinically confirmed diagnosis of osteonecrosis not related to an oncological diagnosis or treatment
- • Patients with medical contraindications for jaw reconstruction combined with immediate implant loading for fixed prosthetic rehabilitation
- • Patients eligible for conventional removable prosthetic rehabilitation
About Az Sint Jan Av
AZ Sint-Jan AV is a leading healthcare institution dedicated to advancing medical research and improving patient outcomes through innovative clinical trials. Located in Bruges, Belgium, the organization is committed to fostering a collaborative environment that encourages scientific inquiry and the development of new therapies. With a multidisciplinary team of experienced professionals, AZ Sint-Jan AV focuses on a wide range of therapeutic areas, ensuring rigorous adherence to ethical standards and regulatory compliance. By prioritizing patient safety and engagement, the institution aims to contribute significantly to the global body of medical knowledge and enhance the quality of care provided to its community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bruges, , Belgium
Patients applied
Trial Officials
Johan Abeloos, MD
Principal Investigator
Department of Oral and Maxillofacial Surgery, General Hospital Saint-John Bruges, Bruges, Belgium
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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