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Search / Trial NCT02661139

Prospective Registry of Prosthodontic Rehabilitation in Oncology Patients Undergoing Jaw Reconstruction

Launched by AZ SINT-JAN AV · Jan 19, 2016

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

Bisphosphonates Jaw Reconstruction Prosthetic Rehabilitation Quality Of Life Monoclonal Antibodies' Targeted Therapy

ClinConnect Summary

This clinical trial is focused on gathering information about patients with head and neck cancer who need jaw reconstruction. The goal is to create a database that tracks important details about patients, their surgeries, dental care, and quality of life over time. This study is specifically looking at patients who have certain conditions affecting their jawbone due to cancer treatment or disease, and who are eligible for special dental implants that can be placed right after their jaw is rebuilt or at a later time.

To participate in this trial, individuals of any age and gender must have a confirmed diagnosis related to their jaw and oral cavity that requires significant surgery. They should also not be suitable for traditional removable dentures. Participants can expect to visit the clinic regularly, where their progress and experiences will be recorded to help improve future treatments for similar patients. It's important to know that this study is currently recruiting participants, and it aims to enhance the understanding of how to better support patients undergoing these complex procedures.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients of all ages
  • Patients of all genders
  • Patients with a histologically or clinically confirmed diagnosis of ORN, MRONJ, as classified by Ruggiero et al. (Ruggiero, et al., 2014) or carcinoma located in the oral cavity and jawbone, requiring segmental or total jaw resection
  • Patients eligible for jaw and oral cavity reconstruction combined with immediate/delayed implant loading for fixed prosthetic rehabilitation
  • Patients not eligible for conventional removable prosthetic rehabilitation
  • Exclusion Criteria:
  • Patients with a clinically confirmed diagnosis of osteonecrosis not related to an oncological diagnosis or treatment
  • Patients with medical contraindications for jaw reconstruction combined with immediate implant loading for fixed prosthetic rehabilitation
  • Patients eligible for conventional removable prosthetic rehabilitation

About Az Sint Jan Av

AZ Sint-Jan AV is a leading healthcare institution dedicated to advancing medical research and improving patient outcomes through innovative clinical trials. Located in Bruges, Belgium, the organization is committed to fostering a collaborative environment that encourages scientific inquiry and the development of new therapies. With a multidisciplinary team of experienced professionals, AZ Sint-Jan AV focuses on a wide range of therapeutic areas, ensuring rigorous adherence to ethical standards and regulatory compliance. By prioritizing patient safety and engagement, the institution aims to contribute significantly to the global body of medical knowledge and enhance the quality of care provided to its community.

Locations

Bruges, , Belgium

Patients applied

0 patients applied

Trial Officials

Johan Abeloos, MD

Principal Investigator

Department of Oral and Maxillofacial Surgery, General Hospital Saint-John Bruges, Bruges, Belgium

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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