Cellular and Molecular Inflammatory Mechanisms Leading to Bone Resorption in Peri-implantitis Vs Periodontitis

Launched by UNIVERSITY OF PARIS 5 - RENE DESCARTES · Jan 22, 2016

Keywords

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Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Beneficiary by national health insurance
• • Age: over 18 year-old
• • Non smoking
• • Good health
• ---For the periimplantitis group:
• • patients formerly treated with a non surgical procedure without antibiotics with at least one functional dental implant with at least on pocket deeper than 5 mm with bleeding on probing and radiographical alveolar bone loss.
• ---For the periodontitis group:
• • patients formerly treated with a non surgical procedure without antibiotics for a generalized severe chronic periodontitis (in accord to Armitage 2009) and needing a resective surgical procedure (periodontal pockets deeper than 5 mm with bleeding on probing)
• ---For the healthy group:
• • patients with good health without periodontal or peri implant disease needing gingivectomy (crown lengthening, esthetic surgery)
• Exclusion Criteria:
• • Smokers
• • Patients treated with antibiotics or NSAID during the last 3 months
• • Patients suffering from a chronic infectious, inflammatory or auto-immune disease (non equilibrated diabetes mellitus, rheumatoid arthritis, spondylarthrosis, Gougerot-Sjögren, Crohn, Behcet, Horton, obesity, chronic end renal disease, cardiopathies....)
• • Pregnant women
• • For the healthy group : bleeding on probing on the site.