Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)

Launched by MAINEHEALTH · Jan 26, 2016

Keywords

ClinConnect Summary

This clinical trial, titled "Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)," is investigating how the body’s immune response and inflammation change after a person has a cardiac arrest. The researchers are particularly interested in understanding how these changes affect brain injury, survival, and recovery in patients. To do this, they will collect blood samples from participants over a week to analyze the immune cells and their behaviors, which can provide insights into the inflammatory processes involved after a cardiac arrest.

To participate in this study, individuals need to be at least 18 years old and must have been admitted to the intensive care unit after experiencing a cardiac arrest. They should also be unresponsive after being resuscitated. Participants will undergo blood tests during their hospital stay, and their health outcomes will be monitored. It’s important to note that those who are critically ill or unable to give consent within 24 hours after resuscitation will not be eligible for this trial. This study aims to improve our understanding of how inflammation affects recovery after cardiac arrest, which could lead to better treatments in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 18 years or older
• • Admitted to the intensive care unit after cardiac arrest episode
• • Unresponsive after resuscitation
• Exclusion Criteria:
• • Moribund / actively dying at the time of evaluation
• • Informed consent cannot be obtained within 24 hours of resuscitation
• • Hemoglobin less than 7.0 g/dL, active high-volume bleeding, or requiring a transfusion