Investigation of the Genetics of Hematologic Diseases

Launched by ST. JUDE CHILDREN'S RESEARCH HOSPITAL · Mar 25, 2016

Keywords

ClinConnect Summary

This clinical trial is focused on understanding the genetic factors that contribute to various blood diseases, such as bone marrow failure syndromes, sickle cell disease, and others. The researchers aim to collect blood samples, tissue, and health information from individuals with these conditions and their family members. By doing this, they hope to uncover the reasons why some people with the same blood disease may experience different levels of severity and how their genetic makeup might influence treatment responses. This study is not designed to provide treatment or diagnosis but rather to gather important data that could lead to better understanding and management of blood diseases in the future.

To participate in this study, you should be someone receiving therapy for a non-cancer blood disorder or be a close family member of such an individual. There are no specific exclusions, so if you're related to someone with these conditions, you might be eligible. Participants can expect to provide samples like blood, urine, or saliva, alongside filling out health questionnaires. This information will be used for research to potentially discover new ways to diagnose and treat blood diseases, making it a vital step toward improving care for patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • An individual (proband) receiving therapy or expert consultation regarding a non-malignant hematologic disorder, MDS or MPN.
• • A biologically-related individual to the identified proband to include: first, second or third degree relatives.
• Exclusion Criteria:
• • None