Chemoradiotherapy in Elderly Patients With Oesophagus Cancer

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON · Apr 6, 2016

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called chemoradiotherapy (CRT) for elderly patients with esophageal cancer who are not able to have surgery. The aim is to see how well this treatment works and if it can be safely given to patients over the age of 75, as most studies have focused on younger patients. Chemoradiotherapy combines radiation therapy with chemotherapy, but it can cause severe side effects, and there isn’t much information on how it affects older patients.

To participate in this trial, patients must be over 75 years old and have a specific type of esophageal cancer. They also need to be in relatively good health, meaning they should have normal blood counts and organ function. If someone joins the study, they will receive the CRT treatment and will be closely monitored for any side effects. This trial is important because it could help improve treatment options for older adults with esophageal cancer.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Esophageal cancer, squamous and adenocarcinoma types, T1-3, N0-1, M1a (TNM 6th),
• • age \> 75 years,
• • WHO status \< 2, Balducci 1, adequate bone marrow reserve, normal renal and hepatic function.
• Exclusion Criteria:
• • age \< 75 years