Pancreas Registry and High Risk Registry

Launched by ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · May 16, 2016

Keywords

ClinConnect Summary

This clinical trial, called the Pancreas Registry and High Risk Registry, is focused on understanding pancreatic diseases, including pancreatic cancer, pancreatitis, and pancreatic cysts. The study aims to gather information from patients who have these conditions or who are at high risk for developing pancreatic cancer, particularly those with a family history of the disease or certain genetic mutations linked to pancreatic cancer. By collecting data about these patients, researchers hope to learn more about how family history and other factors can influence the development of pancreatic diseases.

To participate in this study, you may be eligible if you have a close relative with pancreatic cancer, certain genetic mutations, or a history of pancreatic cysts. Participants will be asked to provide a blood sample, which will help researchers study the genetic factors involved in these conditions. The information collected could lead to better understanding, prevention, and treatment options for pancreatic cancer in the future. If you're interested, you can join this study if you're between the ages of 65 and 74 and speak English or Spanish.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • At least 1 first degree relative affected with Pancreatic Cancer
• • Any of (BRCA1, BRCA2, PALB2, ATM) mutations + 1 family member with Pancreatic Cancer
• • mFAMMM (p16,CDKN2A mutations) + 1 family member with Pancreatic cancer
• • Known mutation carrier for STK11 (Peutz Jeghers Syndrome)
• • Lynch syndrome (HNPCC) + 1 family PDAC
• • Known mutation carrier for Hereditary pancreatitis
• • Individuals with a history of pancreatic cyst(s) (IPMN's) that measure ≥ 1 cm
• Exclusion Criteria:
• • Patients who do not speak English or Spanish
• • Refusal by patient
• • Individuals under the age of 18 years