Prospective Research Rare Kidney Stones (ProRKS)

Launched by MAYO CLINIC · May 20, 2016

Keywords

ClinConnect Summary

The Prospective Research Rare Kidney Stones (ProRKS) trial is studying different hereditary conditions that can lead to kidney stones and chronic kidney disease. The goal is to understand how these conditions affect patients over time by measuring certain markers in blood and urine. By comparing the experiences of different groups, researchers hope to learn more about how these diseases cause kidney problems.

To participate in this study, individuals need to have a diagnosis of one of the following conditions: primary hyperoxaluria, enteric hyperoxaluria, Dent Disease, cystinuria, adenine phosphoribosyltransferase deficiency (APRTd), or Lowe Syndrome. It's important to note that people who have had kidney failure or have received a liver or kidney transplant are not eligible. Participants will undergo tests to measure their health markers and will help researchers gather valuable information that could improve understanding and treatment of these conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Diagnosis of primary hyperoxaluria
• • 2. Diagnosis of enteric hyperoxaluria
• • 3. Diagnosis of Dent Disease
• • 4. Diagnosis of Cystinuria
• • 5. Diagnosis of adenine phosphoribosyltransferase deficiency (APRTd)
• • 6. Diagnosis of Lowe Syndrome
• • 7. Diagnosis of Dent Disease Carrier
• Exclusion Criteria:
• • 1. Prior renal failure
• • 2. History of liver and/or kidney transplant.