Comparative Study of Three Different Embryo Transfer Media in ICSI Cycles

Launched by SOUTH VALLEY UNIVERSITY · Jun 6, 2016

Keywords

ClinConnect Summary

Two or three embryos will be transferred at day 5 after ovum pick-up (OPU).

The patients will be divided randomly (closed envelop method) into 3 groups:

* Group A (50 patients): embryos will be transferred using a medium supplemented with 0.5 mg/mL of hyaluronic acid (EmbryoGlue®, Vitrolife, Sweden) for 20 minutes before intrauterine transfer took place
* Group B (50 patients): embryos will be transferred using a medium of 30% Protein-supplemented Culture Medium (Global total®, Life Global group, Canada) for 20 minutes.
* Group C (50 patients): a novel technique in which embryos will be t...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. Age: 18-35 years
• • 2. Body mass index (BMI): ≤ 30
• • 3. Anti-mullerian hormone (AMH): 1.1 - 3
• • 4. No gynecological problem e.g. fibroid, endometriosis, uterine polyp, hydrosalpinx or adenomysis
• • 5. Male factor: mild to moderate oligo or asthenospermia
• Exclusion Criteria:
• • 1. Age: \<18 years or \>35 years
• • 2. Body mass index (BMI): \>30
• • 3. Anti-mullerian hormone (AMH): \<1.1 or \>3
• • 4. gynecological problem e.g. fibroid, endometriosis, uterine polyp, hydrosalpinx or adenomysis will be excluded
• • 5. Male factor: Abnormal sperm morphology; (globozoospermia and pin-point sperm) and azoospermia; (whether obstructive or non-obstructive) will be excluded
• • 6. Patients with recurrent implantation failure