Treatment of Melasma With Glycolic Acid-Salicylic Acid Peel Versus Glycolic Acid Peel

Launched by BOSTON MEDICAL CENTER · Jun 23, 2016

Keywords

ClinConnect Summary

Melasma is an acquired form of hyperpigmentation that is seen most commonly on the face, characterized by symmetrically distributed brown patches of variable darkness. The cosmetically unattractive nature of this disorder has been shown to negatively affect a patient's quality of life. Unfortunately, the treatment of melasma is challenging and often disappointing. Treatment includes a combination approach with strict sun protection, cosmetic camouflage, topical lightening agents, laser therapy, and chemical peels.

Today, the investigators define chemical peeling as the application of chemi...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Female and males aged 18 or older
• • Subjects with melasma on both sides of the face (forehead or cheek).
• • Subjects in general good health
• • Female of childbearing age will be on a reliable form of contraception during the course of treatment other than oral contraceptive pills or hormonal intrauterine device.
• • Subjects must be willing to sign consent, answer questionnaires, comply with all clinical visits, and use sunscreen and sun-protection.
• • Subjects must be willing to not apply other treatment options for melasma during the course of the study
• Exclusion Criteria:
• • Subjects suffering from other pigmentation disorders.
• • Subjects with known allergy to any components of the peels
• • Subjects who have active uncontrolled disease to facial area (i.e acne).
• • Pregnant women, nursing mothers.
• • Subjects with history of abnormal scaring
• • Subjects who cannot communicate with investigators or who are unlikely to cooperate.
• • Subjects in a situation in which in the opinion of the investigators, may interfere with optimal participation in the study.
• • Subjects who have used chemical peels, microdermabrasion or facial laser treatments in the past 3 months.