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Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation

Launched by FONDATION OPHTALMOLOGIQUE ADOLPHE DE ROTHSCHILD · Aug 29, 2016

Trial Information

Current as of July 09, 2025

Recruiting

Keywords

ClinConnect Summary

The clinical trial titled "Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation" is investigating how specific genetic factors relate to the severity of eye surface conditions in patients with genetic eye disorders. The researchers want to find out if certain genetic changes can help predict how severe a patient's symptoms might be. This study is currently looking for participants of all ages who have a genetic issue affecting the surface of their eyes.

To be eligible for the trial, participants must have a known genetic condition that impacts their ocular surface. However, individuals with conditions like advanced glaucoma, significant vision loss from retinal problems, or those who are pregnant or breastfeeding cannot join the study. If you choose to participate, you will help researchers understand these genetic connections better, which could lead to improved treatments for future patients.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • genetic pathology of ocular surface
  • Exclusion Criteria:
  • Agonal glaucoma
  • Low vision mostly related to retinal pathology
  • Pregnant or breast feeding patient

About Fondation Ophtalmologique Adolphe De Rothschild

The Fondation Ophtalmologique Adolphe de Rothschild is a leading French institution dedicated to advancing ophthalmic research and patient care. Renowned for its commitment to innovation in eye health, the foundation conducts cutting-edge clinical trials aimed at improving treatments for various ocular conditions. With a multidisciplinary team of experts, the foundation collaborates with academic and industry partners to enhance understanding of eye diseases and develop novel therapeutic solutions, ultimately striving to improve patient outcomes and quality of life in ophthalmology.

Locations

Paris, , France

Patients applied

0 patients applied

Trial Officials

Anna GEMAHLING, MD

Principal Investigator

Hôpital Fondation Adolphe de Rothschild

Eric GABISON, MD

Principal Investigator

Hôpital Bichat (AP-HP)

Dominique BREMOND-GIGNAC, MD

Principal Investigator

Hopital Necker-enfants malades (AP-HP)

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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