Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation
Launched by FONDATION OPHTALMOLOGIQUE ADOLPHE DE ROTHSCHILD · Aug 29, 2016
Trial Information
Current as of July 09, 2025
Recruiting
Keywords
ClinConnect Summary
The clinical trial titled "Limbal Stem Cell Deficiency of Genetic Origin: Genotype-phenotype Correlation" is investigating how specific genetic factors relate to the severity of eye surface conditions in patients with genetic eye disorders. The researchers want to find out if certain genetic changes can help predict how severe a patient's symptoms might be. This study is currently looking for participants of all ages who have a genetic issue affecting the surface of their eyes.
To be eligible for the trial, participants must have a known genetic condition that impacts their ocular surface. However, individuals with conditions like advanced glaucoma, significant vision loss from retinal problems, or those who are pregnant or breastfeeding cannot join the study. If you choose to participate, you will help researchers understand these genetic connections better, which could lead to improved treatments for future patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • genetic pathology of ocular surface
- Exclusion Criteria:
- • Agonal glaucoma
- • Low vision mostly related to retinal pathology
- • Pregnant or breast feeding patient
About Fondation Ophtalmologique Adolphe De Rothschild
The Fondation Ophtalmologique Adolphe de Rothschild is a leading French institution dedicated to advancing ophthalmic research and patient care. Renowned for its commitment to innovation in eye health, the foundation conducts cutting-edge clinical trials aimed at improving treatments for various ocular conditions. With a multidisciplinary team of experts, the foundation collaborates with academic and industry partners to enhance understanding of eye diseases and develop novel therapeutic solutions, ultimately striving to improve patient outcomes and quality of life in ophthalmology.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Paris, , France
Patients applied
Trial Officials
Anna GEMAHLING, MD
Principal Investigator
Hôpital Fondation Adolphe de Rothschild
Eric GABISON, MD
Principal Investigator
Hôpital Bichat (AP-HP)
Dominique BREMOND-GIGNAC, MD
Principal Investigator
Hopital Necker-enfants malades (AP-HP)
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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