Filgotinib in Combination With Methotrexate in Adults With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Methotrexate
Launched by GILEAD SCIENCES · Aug 31, 2016
Trial Information
Current as of August 31, 2025
Completed
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Key Inclusion Criteria:
- • Have a diagnosis of rheumatoid arthritis (RA) \[2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria\] , and are ACR functional class I-III.
- • Have ≥ 6 swollen joints (from a swollen joint count based on 66 joints (SJC66)) and ≥ 6 tender joints (from a tender joint count based on 68 joints (TJC68)) at both screening and Day 1.
- • Ongoing treatment with a stable dose of MTX
- Key Exclusion Criteria:
- • Previous treatment with any janus kinase (JAK) inhibitor
- • NOTE: Other protocol defined Inclusion/ Exclusion criteria may apply.
About Gilead Sciences
Gilead Sciences is a leading biopharmaceutical company focused on the discovery, development, and commercialization of innovative medicines to address unmet medical needs. With a strong emphasis on antiviral therapies, particularly for HIV, hepatitis B, hepatitis C, and influenza, Gilead leverages advanced research and development capabilities to drive breakthroughs in treatment and care. The company is committed to improving patient outcomes through rigorous clinical trials, fostering collaborations with healthcare professionals, and engaging in partnerships to enhance global health. Gilead's dedication to scientific excellence and patient-centric approaches positions it at the forefront of the biopharmaceutical industry.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Jacksonville, Florida, United States
Saint Louis, Missouri, United States
San Antonio, Texas, United States
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Kansas City, Kansas, United States
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Haifa, , Israel
Tel Hashomer, , Israel
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Detroit, Michigan, United States
Dallas, Texas, United States
Mendoza, , Argentina
Merksem, , Belgium
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Warszawa, , Poland
Wroclaw, , Poland
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Durban, , South Africa
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Phoenix, Arizona, United States
Clearwater, Florida, United States
Orlando, Florida, United States
Lexington, Kentucky, United States
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Huntsville, Alabama, United States
Charleston, South Carolina, United States
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Tainan, , Taiwan
Auckland, , New Zealand
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Bydgoszcz, , Poland
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Lviv, , Ukraine
Odessa, , Ukraine
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Covina, California, United States
Haskovo, , Bulgaria
Plovdiv, , Bulgaria
Sofia, , Bulgaria
Katowice, , Poland
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Plantation, Florida, United States
Tupelo, Mississippi, United States
Duncansville, Pennsylvania, United States
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New Port Richey, Florida, United States
Cumberland, Maryland, United States
Varna, , Bulgaria
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Chiangmai, , Thailand
Hamilton, , New Zealand
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Kyoto, , Japan
Hyderabad, , India
Rimavska Sobota, , Slovakia
Tokyo, , Japan
Genk, , Belgium
Fukuoka, , Japan
Kumamoto, , Japan
Shizuoka, , Japan
Corpus Christi, Texas, United States
Białystok, , Poland
Beaumont, Texas, United States
Leiden, , Netherlands
Wheaton, Maryland, United States
Uherske Hradiste, , Czechia
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Palm Desert, California, United States
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Belgrade, , Serbia
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Kemerovo, , Russian Federation
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Elizabethtown, Kentucky, United States
Ostrava, , Czechia
Distrito Federal, , Mexico
Nizhniy Novgorod, , Russian Federation
Webster, Texas, United States
Vinnytsya, , Ukraine
Kherson, , Ukraine
Wakayama, , Japan
San Miguel De Tucumán, , Argentina
Toruń, , Poland
Saint Clair Shores, Michigan, United States
Mesquite, Texas, United States
Shinjuku Ku, , Japan
Izumo, , Japan
Narashino, , Japan
Tokorozawa, , Japan
Takaoka, , Japan
Surat, , India
Yokohama Shi, , Japan
Gurgaon, , India
Caba, , Argentina
Miami Lakes, Florida, United States
Doncaster, , United Kingdom
Visakhapatnam, , India
Hemet, California, United States
Victorville, California, United States
Prievidza, , Slovakia
Warrington, , United Kingdom
Dnipro, , Ukraine
Târgu Mureş, , Romania
Jeonju, , Korea, Republic Of
Szentes, Csongrad, Hungary
Oradea, Bihor, Romania
Bucharest, Bucuresti, Romania
Suita Shi, , Japan
Newtown, , New Zealand
Keelung, , Taiwan
Vidin, , Bulgaria
Nowa Sól, , Poland
Tsukuba Shi, , Japan
Sayama Shi, , Japan
Elbląg, , Poland
Nagasaki Shi, , Japan
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Sasebo Shi, , Japan
Songkla, , Thailand
Iruma Gun, , Japan
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Kitakyushu Shi, , Japan
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Dobrich, , Bulgaria
Kalocsa, Bacs Kiskun, Hungary
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Srikakulam, , India
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Topol'cany, , Slovakia
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Shibata City, , Japan
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Luts'k, , Ukraine
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Patients applied
Trial Officials
Gilead Study Director
Study Director
Gilead Sciences
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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