Transcranial Magnetic Stimulation (TMS) for Upper Limb Dysfunction in Spinal Cord Injury: a Feasibility Study
Launched by SHEFFIELD TEACHING HOSPITALS NHS FOUNDATION TRUST · Sep 22, 2016
Trial Information
Current as of August 25, 2025
Completed
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Aged 18-70 years old inclusive
- • Traumatic and non-traumatic tetraplegic patient following chronic incomplete (AIS C or D) SCI injury (sustained at least three months ago)
- • Referred to the Sheffield Spinal Injuries Centre
- • Be able to provide written informed consent or verbal consent in the presence of an independent witness
- • Spasticity affecting upper limbs with a Modified Ashworth scale (MAS) 2 or above
- • Stable medical treatment for at least 1 week before and 1 week after TMS application
- • Stable medical condition
- Exclusion Criteria:
- • Aged less than 18 years old
- • Lack the mental capacity to consent
- • Ventilated patients with sedation
- • Very acute (\<3 months) SCI patients
- • Implanted electrical devices such as pacemakers, Concomitant neurological conditions, including any history of epilepsy
- • Significant joint-related limitation of passive range of movement
- • Unable to attend all TMS sessions
- • Pregnancy
- • Inability to tolerate TBS
- • Significant upper limb contractures
About Sheffield Teaching Hospitals Nhs Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust is a leading healthcare institution in the UK, dedicated to delivering high-quality patient care, advancing medical research, and fostering education and training in the health sector. As a prominent sponsor of clinical trials, the Trust collaborates with various stakeholders to facilitate innovative research initiatives that aim to improve treatment outcomes and enhance patient safety. With a commitment to excellence, the organization leverages its extensive clinical expertise and resources to support the development of new therapies and interventions, ultimately contributing to the advancement of healthcare practices both locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Sheffield, South Yourkshire, United Kingdom
Patients applied
Trial Officials
Ram Hariharan, MD
Study Chair
Sheffield Teaching Hospitals NHS Foundation Trust
Ali Gharooni
Principal Investigator
Sheffield Teaching Hospital NHS Foundation Trust. University of Sheffield.
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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